In arid and semi-arid lands, people eats many kinds of spices. Capsaicin is one effect active component of spices. Previously we demonstrated that capsaicin induced tight junction (TJ) opening in human intestinal Caco-2 cells. We showed that the increase of TJ permeability was involved in actin polymerization. However the underlying mechanisms are unclear. The major aims of this study were to d...

Four commonly used spices plants in Iran were evaluated for cytotoxicity effect using Brine Shrimp Lethality (BSL) assay. Essential oils and various extracts of Heracleum persicum, Nigella arvensis, Cinnamomum zeylanicum and Zingiber officinale were assessed by two methods of disk and solution of BSL. Data were processed in probit-analysis program to estimate LC50 values. All of the tested frac...

1,2 Department of Veterinary Public Health, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala, India 680 651 ________________________________________________________________________________________ Abstract Investigations were carried out to study the inhibitory effect of ginger (Zingiber officinale) and garlic (Allium sativum) extracts at 0.5, 1.0, 2.0, 7.0 and 10.0 per cen...

Traditional Indian medicine (ayurveda) is becoming increasingly popular, with many chronic conditions responding to it well. Most patients begin to take conventional medications as soon as their diagnoses are made, so ayurvedic treatments are usually undergone alongside and/or after conventional medical approaches. A detailed knowledge of the action of food, spices, and medicinal plants is need...

Inflammatory bowel diseases (IBDs), consisting mainly of ulcerative colitis (UC) and Crohn's disease (CD), are important immune-mediated diseases of the gastrointestinal tract. The etiology of the disease includes environmental and genetic factors. Its management presents a constant challenge for gastroenterologists and conventional surgeon. 5-Amninosalicylates, antibiotics, steroids, and immun...

A number of Indian spices are used as rejuvenators as well as for treating various disease conditions. They may be tonics, antipyretics, aphrodisiacs, expectorants, hepatoprotectives, antirheumatics, diuretics, etc. Cuminum cyminum and Carum carvi are the sources of cumin and caraway seeds respectively, which have been used since antiquity for the treatment of various indications in traditional...

Background About 3-4 % of the population in industrial countries are adversely affected by food allergens [1]. Spice allergy represents 2 % of these cases. Spices are one of the most attractive ingredients to add a unique taste to food and are often used in blends. Spice blends in general consist of a variety of potentially allergenic ingredients which complicates the identification of the part...

In Egypt, liver diseases represent a national endemic crises, annually increasing to affect younger people. About 25% of population are sharing at least one of the liver problems; cirrhosis, hepatitis C virus HCV and/or hepatocellular carcinoma HCC with 100,000 death rate annually. Screening of 50 Egyptian spices, vegetables and wild plants for cytotoxicity against HepG2, successfully uncovered...

The antioxidant activity and total phenolic content of some spices (M. piperita L., R. coriaria L., T. spicata, S. officinalis, R. officinalis L., C. ovata L., O. vulgare L., L. nobilis L. and C. annum L.) were determined. The higher TEAC values (mmol TE/g extract) were obtained for sage (1.783) and rosemary (1.241). The IC value (mg/ml) ranged between 0.103-4.082 for mint and capers, respectiv...

Irradiation is a preservation technology used to improve the safety and hygienic quality of food. Aim of this study was to assess the applicability and validity of the microbiological screening method direct epifluorescence filter technique (DEFT)/aerobic plate count (APC) (EN 13783:2001) for the identification of irradiated herbs and spices. Tests on non-irradiated and irradiated samples of dr...