The effect of fatty acids and ketones on 35S04 incorporation into the chondromucoproteins of embryonic chicken cartilage was studied in vitro. Both the nonstimulated incorporation (that occurring in media without added serum) and sulfation factor stimulated incorporation (that occurring in media with 5.0% rat serum added) were investigated. Butyrate and octanoate, from 0.01 mM to 1.0 mu, had mi...