objective: this study was conducted with the aim to investigate and compare iranian produced and foreign oxytocin for use in induction of labor. materials and methods: this random clinical trial was conducted on a population of 198 pregnant women with live fetus and cephalic presentation and conditions conducive to induction of labor, monitored by obstetricians and gynecologists. they were rand...

The present study aimed to evaluate the GSH and MDA levels in dog’s serum vital organs of aborted fetuses, after application two abortifacient. Animals group I (n = 6) were treated twice with subcutaneous injection 10 mg/kg aglepristone II 3) received prostaglandin F2α at a dose 125 μg/kg every 12 hours until abortion process completed. Hematologic examinations sedimentation rates performed bit...

Rupture of the extraembryonic membranes that form the gestational sac in humans is a typical feature of human parturition. However, preterm premature rupture of membranes (PPROM) occurs in approximately 1% of pregnancies, and is a leading cause of preterm birth. Conversely, retention of an intact gestational sac during parturition in the form of a caul is a rare occurrence. Understanding the mo...

In many mammals, hormonal fluctuations during pregnancy and parturition produce neurochemical events that are necessary for the transition from a non-maternal state to a maternal state that occurs when infants are born. However, the nature of these events is mostly unknown. We investigated whether changes in dopamine (DA) and serotonin (5-HT) activity within the preoptic area (POA) and striatum...

Changes in brain oxytocin receptor (OTR) binding sites during the course of pregnancy may influence the sudden onset of maternal behavior in female rats at parturition. In situ hybridization was used to identify changes in OTR messenger ribonucleic acid (mRNA) expression during pregnancy and parturition. Two patterns of mRNA regulation were observed. Relative to diestrus virgin control females,...

At parturition, dairy cows experience a 70% reduction in plasma IGF-I. This reduction coincides with decreased abundance of GHR1A, the liver-specific transcript of the growth hormone receptor (GHR) gene, suggesting impaired growth hormone-dependent synthesis of IGF-I. It is not immediately obvious that the periparturient reduction in GHR1A is sufficient to reduce hepatic GHR abundance. This is ...

The aim of the study was to establish differences in energetic, protein, and enzymatic profiles in ewes bearing single or twin lambs. Blood samples were collected from 40 ewes of improved Wallachian breed at the beginning of pregnancy, one month before parturition, shortly after parturition, and one month after parturition. Significantly (P<0.01) lower glucose levels (2.13 vs. 2.59 mmol.l) in t...