Background and Aims: Patients with FH showed impaired immunosuppressive response associated increased inflammation. We tested Adoptive Cell Therapy (ACT) Treg engineered to selectively migrate in the atherosclerotic plaque dampen immune-inflammatory arterial wall.

This study aimed to investigate the molecular mechanism of Picrasma quassioides Benn against inflammation by means network pharmacology. The paper will provide a reference for multi-target and multi-channel treatment with traditional Chinese medicine. Through screening analysis, 11 active ingredients 109 anti-inflammation prediction targets were obtained constructed compound-target network. suc...

background: diabetes causes the increased concentration of circulatory cytokines as a result of inflammation. considering that pomegranate juice (pj) is known to have antioxidant and anti-inflammatory properties, the purpose of this study was to determine the effects of pj consumption on markers of inflammation in patients with type 2 diabetes (t2d). materials and methods: in a randomized, doub...

introduction: due to side effects of antiinflammatory drugs such as dexamethasone and indomethacin, there is a less tendency to use them. on the other hand, the use of medicinal plants has been common in the treatment of inflammation since ancient times and also, using of the plants is increasing. present research investigated the antiinflammatory effect of the hydroalcoholic extract of capitol...

ocular involvement is seen in approximately 25% of patients with sarcoidosis. uveitis is the most common ocular manifestation, but sarcoidosis may involve any part of the eye. orbital manifestations of sarcoidosis are uncommon with few series in the literature. a 65-year-old woman presented with redness of the right eye and painless, unilateral eyelid swelling. orbital scanning revealed mass in...

traumatic brain injury (tbi) is a significant public health concern in our country, because of placing in top three most common causes of death and substantial direct and indirect costs to society. the incidence of tbi in our country is 1.7 times of international incidence. traumatic brain injury induced by primary and secondary mechanisms that give rise to death and neurologic morbidity in pat...