Diclofenac sodium has been used for its anti-inflammatory actions for about 28 years, but since all the non-steroidal anti-inflammatory drugs (NSAIDs) suffer from the lethal gastro intestinal (GI) toxicities, diclofenac sodium is not an exception. The free –COOH group is thought to be responsible for the GI toxicity associated with all traditional NSAIDs. In the present research, the main motto...

In attempt to find new pharmacologically active molecules, we report here the synthesis and in vitro anti-inflammatory activity of various 1-[5-(substituted phenyl)-1-phenyl-4,5dihydro-1H-pyrazol-3-yl]-5-phenyl-1H-tetrazole (IV a-h).The anti-inflammatory activity of title compounds were examined by denaturation of proteins method. All the compounds exhibited weak to potent anti-inflammatory act...

Spatiotemporal analysis of the inflammatory response has been limited by the difficulties of in vivo imaging and reconstitution of inflammation in vitro. Here, we present a novel method for establishing in vivo-like inflammatory models in a microfluidic device and quantitatively measuring the three-dimensional transmigration of neutrophils during the inflammatory process. This enabled us to con...

s The present study is an endeavour to evaluate anti inflammatory and antioxidant activities of ehtanolic extract of steam bark of Zanthoxylum armatum. In vivo anti inflammatory activity was evaluated in wistar species of rats by using carrageenin induced paw edema, where as in vitro antioxidant activity was performed by DPPH free radical method. The plant extract exhibited significant anti-inf...

The leaf extract of Murraya koenigii were assessed for In vitro Anti Inflammatory activity by HRBC membrane stabilization method and Denaturation of protein inhibition method. The presence of flavanoids and carbazole alkaloids has been reported earlier in M.koenigii. Since the flavanoids and carbazole alkaloids have remarkable anti-inflammatory activity, so the present work aims at evaluating t...

The triazole nucleus is an important part of the therapeutically interesting drug candidate as antimicrobial, analgesic, anticancer, anticonvulsant and anti-inflammatory agents. Therefore, a number of 1,2,3& 1,2,4-triazole derivatives were synthesized. The structures of these compounds were characterized by means of FT-IR, H-NMR, and elemental analysis. All the compounds were evaluated for anti...

Caesalpinia bonduc possess anti-inflammatory, anthelmintic, digestive, stomachic properties. The present study investigated anti-inflammatory and in vitro anticancer studies of stem bark of C.bonduc. The in vitro antiinflammatory study of different extracts were done by Protein denaturation method. The total ethanolic extract of stem bark of C.bonduc was investigated for in vivo anti-inflammato...

   Licorice, the oldest Chinese traditional medicine, is widely used in the treatment of human diseases. Due to the deficiency of wild resource, selecting and breeding becomes a key issue to expanding the supply of licorice. Spaceflight technology will become a new method for medicinal plants. The aim of this study was to investigate the effect of spaceflight on the components and anti-inflamma...