نتایج جستجو برای: influenza virus nucleoprotein
تعداد نتایج: 432895 فیلتر نتایج به سال:
were positive for the hemagglutinin (HA) and neuraminidase genes of avian influenza A (H7N9) virus. Of 6 environmental samples, 5 were positive for (H7N9) virus HA genes. No (H7N9) virus HA antibodies were detected from paired serum samples from all 18 close contacts. Two virus strains were isolated: 1 from a patient specimen (A/Zhenjiang/1/2013) and 1 from a chicken cage specimen (A/environmen...
The outbreak of human infections caused by novel avian-origin influenza A(H7N9) in China since March 2013 underscores the need to better understand the pathogenicity and transmissibility of these viruses in mammals. In a ferret model, the pathogenicity of influenza A(H7N9) was found to be less than that of an influenza A(H5N1) strain but comparable to that of 2009 pandemic influenza A(H1N1), ba...
The negative sense RNA genome of influenza A virus is transcribed and replicated in the nuclei of infected cells by the viral RNA polymerase. Only four viral polypeptides are required but multiple cellular components are potentially involved. We used fluorescence recovery after photobleaching (FRAP) to characterise the dynamics of GFP-tagged viral ribonucleoprotein (RNP) components in living ce...
Influenza A virus causes recurring seasonal epidemics and occasional influenza pandemics. Because of changes in envelope glycoprotein Ags, neutralizing Abs induced by inactivated vaccines provide limited cross-protection against new viral serotypes. However, prior influenza infection induces heterosubtypic immunity that accelerates viral clearance of a second strain, even if the external protei...
Objective: Influenza A virus infections are still a major health problem and the choices available for the control and treatment of the disease are limited. This research evaluated in vitro and in vivo antiviral effects of Peganum harmala L. seeds (PHS) extract against influenza A virus. Materials and Methods: In this research, in vitro anti-influenza A virus activity of the extract was assesse...
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