نتایج جستجو برای: inha
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Multidrug-resistant strains of Mycobacterium tuberculosis seriously threaten tuberculosis (TB) control and prevention efforts. Molecular studies of the mechanism of action of antitubercular drugs have elucidated the genetic basis of drug resistance in M. tuberculosis. Drug resistance in M. tuberculosis is attributed primarily to the accumulation of mutations in the drug target genes; these muta...
Correspondence to Jin-Soo Lee, M.D. Department of Internal Medicine, Inha University School of Medicine, 27 Inhang-ro, Jung-gu, Incheon 400-711, Korea Tel: +82-32-890-3616, Fax: +82-32-882-6578, E-mail: [email protected] Ji Hyeon Baek and Yu Bin Seo equally contributed to this work. Copyrightc 2014 The Korean Association of Internal Medicine This is an Open Access article distributed under the...
Inhibition of the Mycobacterium tuberculosis enoyl acyl carrier protein reductase InhA by arylamides
Department of Internal Medicine, Seoul St. Mary’s Hospital, Department of Internal Medicine, Seoul National University Hospital, Seoul, Department of Internal Medicine, Inha University Hospital, Incheon, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicin...
515 Received: May 19, 2009. Revised: May 28, 2009. Accepted: June 8, 2009. Corresponding author: Jeong Uk Han, M.D., Department of Anesthesiology and Pain Medicine, Inha University Hospital, 7-206, Sinheung-dong 3ga, Jung-gu, Incheon 400-711, Korea. Tel: 82-32-890-3968, Fax: 82-32-8812477, E-mail: [email protected] Copyright c Korean Society of Anesthesiologists, 2009 cc This is an open-access a...
804 Ann Dermatol Received September 9, 2016, Revised October 22, 2016, Accepted for publication October 31, 2016 Corresponding author: Won Park, Division of Rheumatology, Department of Internal Medicine, Inha University, 366 Seohae-daero, Jung-gu, Incheon 22332, Korea. Tel: 82-32-890-3483, Fax: 82-32-8902237, E-mail: [email protected] This is an Open Access article distributed under the terms ...
A series of isoniazid derivatives bearing a phenolic or heteroaromatic coupled frame were obtained by mechanochemical means. Their pH stability and their structural (conformer/isomer) analysis were checked. The activity of prepared derivatives against Mycobacterium tuberculosis cell growth was evaluated. Some compounds such as phenolic hydrazine 1a and almost all heteroaromatic ones, especially...
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