We investigated the inhibitory effects of antibacterial, biocidal, and antifungal agents against Fusarium spp. Seven Fusarium spp: four F. falciforme (Fusarium solani species complex), one Fusarium spp, one Fusarium spp. (Fusarium incarnatum-equiseti species complex), and one F. napiforme (Gibberella fujikuroi species complex), isolated from eyes with fungal keratitis were used in this study. T...

use of herbal extracts and essences as natural antibacterial compounds has become increasingly popular for the control of oral infectious diseases. therefore, finding natural antimicrobial products with the lowest side effects seems necessary. the present study sought to assess the effect of punica granatum l. water extract on five oral bacteria and bacterial biofilm formation on orthodontic wi...

background and objectives: bacterial resistance to antibiotics has motivated the researchers to evaluate the novel anti-bac- terial compounds such as some thiazole and imidazole derivatives. thereby, in this work, we investigated the anti-bacterial effects of one new thiazole and two new imidazole derivatives on bacillus cereus , listeria monocytogenes , escherichia coli, salmonella typhimurium...

background and objectives: this study was designed to evaluate the activity of quercus infectoria galls extract (qifge) on virulence factor production and inhibition of quorum sensing (qs) in pseudomonas aeruginosa. materials and methods: minimum inhibitory concentration (mic) of qifge against 5 strains of p. aeruginosa was determined. the extract at sub-mic was used to determine biofilm format...

Virus nucleoprotein (NP) is an emerging target for drug development for Influenza. We designed benzamide derivatives as new inhibitors of NP that demonstrate good potency in blocking influenza A. Screening revealed that compound 39 was the most potent molecule in the series, exhibiting IC50 values of 0.46 and 0.27 μM in blocking the replication of H3N2 (A/HK/8/68) and (A/WSN/33) influenza A vir...

Anderson & Green (2001) have recently shown that using an adaptation of the go-no go task, participants can voluntarily inhibit the retrieval of specific memories. We present three experiments in which we try to determine the degree of automaticity involved, and the role of the previous prime-target relation on the development of this inhibitory process. In the first two experiments we manipula...

Interferon-induced transmembrane protein 1 (IFITM1) is an essential mediator of interferon-g-induced antiproliferation. Here, we reported the interaction between IFITM1 and caveolin-1 (CAV-1), and their inhibitory regulatory function on extracellular signal-regulated kinase (ERK). The immunofluorescence staining result showed that IFITM1 localized in caveolae of the plasma membrane and could in...

Sepsis can cause myocardial dysfunction, which contributes to the high mortality of sepsis. Hypertonic saline (HS) has been reported to increase myocardial contractility in sepsis. In the present study, mechanisms of action of HS resuscitation (4 mL of 7.5% NaCl per kilogram) on cardiac function have been evaluated in septic rats. HS was administered 1 h after LPS (10 mg/kg, i.v.) challenge. Th...

Background and Objective: Acute microbial diarrheal diseases are the major public health problems in the developing countries. People affected by diarrheal diseases have the lowest financial resources and poorest hygienic facilities. Children under five, primarily in Asian and African countries, are mostly the subjects affected by microbial diseases transmitted through water.<b...