نتایج جستجو برای: inosine triphosphatase
تعداد نتایج: 8370 فیلتر نتایج به سال:
Previous work has shown that 6-thioguanine (TGua) is an effective inducer of differentiation of Friend and HL-60 leukemia cells which lack hypoxanthine-guanine phosphoribosyltransferase but is at best only weakly active in inducing maturation in parental wild-type cells. Studies in wild-type and mutant HL-60 cells have provided evidence that the free-base TGua is the form of this drug that indu...
Neurogenic detrusor overactivity and the associated loss of bladder control are among the most challenging complications of spinal cord injury (SCI). Anticholinergic agents are the mainstay for medical treatment of detrusor overactivity. However, their use is limited by significant side effects such that a search for new treatments is warranted. Inosine is a naturally occurring purine nucleosid...
Abstract Background Inosine monophosphate dehydrogenase-1 is the target of mycophenolate mofetil. This research investigated association between gene polymorphism inosine and effectiveness mofetil therapy in neuromyelitis optica spectrum disorder patients. Methods Fifty-nine patients accepted Mycophenolate Mofetil for 1 year at least were divided into two groups: relapsing (n=21) non-relapsing ...
The Equilibria for the Inosine–Calcium Hydroxide–Water and Inosine–Strontium Hydroxide–Water Systems
Membrane vesicles were prepared by osmotic lysis of spheroplasts from M13-infected Escherichia coli. Reduced nicotinamide adenine dinucleotide (NADH) oxidase (reduced NAD: oxidoreductase, EC 1.6.99.3) and Mg2+-Ca2+-activated adenosine triphosphatase (ATP phosphohydrolase, EC 3.6.1.3), which are normally localized to the inner surface of the cytoplasmic membrane, were 50% acceesible to their pol...
1. The activity of a Mg(2+)-dependent Na(+)-plus-K(+)-activated adenosine triphosphatase and the concentrations of nicotinamide nucleotide coenzymes have been measured in the immature parotid glands of young lambs and in the actively secreting glands of adult sheep. 2. The activity of the adenosine triphosphatase increased during development and attained relatively high levels in the mature sec...
Triphenylsulphonium ions inhibit mitochondrial oxidative phosphorylation and adenosine triphosphatase activity. The site of action is on the soluble F1 adenosine triphosphatase component. Triphenylsulphonium ions also inhibit electron transfer in the NAD-cytochrome b region of the respiratory chain. In both types of inhibition, triphenylsulphonium ions are effective at low concentrations, half-...
The suppressive action of acyclovir and inosine pranobex was compared in a randomised double blind controlled trial in patients with frequently recurring genital herpes. Fourteen patients received acyclovir and 17 inosine pranobex. Treatment continued for 12 weeks. The time to the first recurrence was significantly longer and the frequency of recurrences significantly less in the recipients of ...
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