In this paper we obtain general integral formulas for probabilities in the asymmetric simple exclusion process (ASEP) on the integer lattice Z with nearest neighbor hopping rates p to the right and q = 1−p to the left. For the most part we consider an N -particle system but for certain of these formulas we can take the N → ∞ limit. First we obtain, for the N -particle system, a formula for the ...

We have analyzed the fate of several integral membrane proteins of the nuclear envelope during mitosis in cultured mammalian cells to determine whether nuclear membrane proteins are present in a vesicle population distinct from bulk ER membranes after mitotic nuclear envelope disassembly or are dispersed throughout the ER. Using immunofluorescence staining and confocal microscopy, we compared t...

We describe the horizon of a quantum black hole in terms of a dynamical surface which defines the boundary of space-time as seen by external static observers, and we define a path integral in the presence of this dynamical boundary. Using renormalization group arguments, we find that the dynamics of the horizon is governed by the action of the relativistic bosonic membrane. From the thermodynam...

Using atomic-scale molecular dynamics simulations, we consider the intrinsic cell membrane potential that is found to originate from a subtle interplay between lipid transmembrane asymmetry and the asymmetric distribution of monovalent salt ions on the two sides of the cell membrane. It turns out that both the asymmetric distribution of phosphatidylcholine (PC) and phosphatidylethanolamine (PE)...

The membrane surfaces within the rod outer segment of the toad, Bufo marinus, were exposed by rapid-freezing followed by freeze-fracture and deep-etching. Platinum-carbon replicas of disk membranes prepared in this way demonstrate a distinct sidedness. The membrane surface that faces the lumen of the disk shows a fine granularity; particles of approximately 6 nm are packed at a density of appro...

Despite the ubiquity of transbilayer asymmetry in natural cell membranes, the vast majority of existing research has utilized chemically well-defined symmetric liposomes, where the inner and outer bilayer leaflets have the same composition. Here, we review various aspects of asymmetry in nature and in model systems in anticipation for the next phase of model membrane studies.

Nanodiscs are a new class of model membranes that are being used to solubilize and study a range of integral membrane proteins and membrane-associated proteins. Unlike other model membranes, the Nanodisc bilayer is bounded by a scaffold protein coat that confers enhanced stability and a narrow particle size distribution. The bilayer diameter can be precisely controlled by changing the diameter ...

We demonstrate that tunable attractive (bonding) and repulsive (anti-bonding) forces can arise in highly asymmetric structures coupled to external radiation, a consequence of the bonding/anti-bonding level repulsion of guided-wave resonances that was first predicted in symmetric systems. Our focus is a geometry consisting of a photonic-crystal (holey) membrane suspended above an unpatterned lay...

Abstract This study investigated the separation of bovine serum albumin using a novel matrix mixed membrane composed poly vinyl pyrrolidone and (phenylene ether sulfone)/Nano-silver. The responsive bare modified PEES/Nano-silver membranes were evaluated morphology, wettability, XRD ATR-FTIR. molecular weight cut-off (MWCO), water content, mean pore radius, porosity, pure flux used to evaluate p...