We studied the influence of defect density in multilayer graphene sheets on intercalation Li ions by means x-ray photoelectron spectroscopy. The was prepared chemical vapor deposition Ni substrates. at room temperature results immediate intercalation, while additional annealing 300 °C partially removes from sample surface. found that varying over several orders magnitude does not process. propo...

Recently potassium-ion batteries have been proposed as a promising next generation battery technology owing to cost effectiveness and wide range of electrode materials well electrolytes available. Potassium bis(fluorosulfonyl)imide (KFSI) in monoglyme (DME) is one potential electrolyte, wherein the K+ solvation heavily depends on salt concentration strongly affects electrochemistry. Pure interc...

Three groups of doxorubicin and daunorubicin analogues, differing by their substituents on the chromophore and sugar moieties, were used in this study. The 3'-A'-unsubstituted (Group I), 3'-/V-acyl (Group 2), and .V-,V-alkyl (Group 3) analogues were tested for: (a) in vivo antitumor activity and in vitro cytotoxicity; (b) cellular or tissue uptake and meta bolic conversion; (c) strength of DNA ...

Flavonoids and other polyphenolic compounds have been shown to inhibit human topoisomerase IB (topo I) through both inhibition of relaxation activity and through stabilization of the cleavable complex (poisoning). Some flavonoids have also been shown to intercalate DNA, and an association of topoisomerase inhibition with intercalation has been noted. We surveyed 34 polyphenolic compounds, prima...

The DNA-intercalating chromophore [Ru(phen)(2)dppz](2+) has unique photophysical properties, the most striking of which is the "light-switch" characteristic when binding to DNA. As a dimer, it acts as a molecular staple for DNA, exhibiting a remarkable double-intercalating topology. Herein, we report femtosecond dynamics of the monomeric and the covalently linked dimeric chromophores, both free...

The first proposed hypothesis about the mechanism of chloroquine (CQ) action on malaria parasites is DNA intercalation hypothesis which indicates that the site of CQ action is within nucleus. Later on the interest of research was shifted from nucleus to lysosome due to the report of CQ accumulation within lysosome. The current opinions about CQ action and resistance are mainly based on the resu...

Three groups of doxorubicin and daunorubicin analogues, differing by their substituents on the chromophore and sugar moieties, were used in this study. The 3'-N-unsubstituted (Group 1), 3'-N-acyl (Group 2), and 3'-N-alkyl (Group 3) analogues were tested for: (a) in vivo antitumor activity and in vitro cytotoxicity; (b) cellular or tissue uptake and metabolic conversion; (c) strength of DNA inte...