نتایج جستجو برای: interleukin 1 receptor antagonist protein
تعداد نتایج: 3928682 فیلتر نتایج به سال:
The cytokine interleukin (IL)-11 has been shown to play a role in promoting fibrosis and cancer, including lung adenocarcinoma, garnering interest as an attractive target for therapeutic intervention. We used combinatorial methods engineer IL-11 variant that binds with higher affinity the receptor stimulates enhanced receptor-mediated cell signaling. Introduction of two additional point mutatio...
BACKGROUND Acute Coronary Syndromes account for 15% of deaths in the UK, and patients remain at significant risk of re-admission for future complications and death. Pathologically the underlying process of atherosclerosis is driven by inflammatory mechanisms, which are activated in ACS patients. Previous studies have investigated the role of inflammatory markers in this process, including inter...
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