نتایج جستجو برای: intestines

تعداد نتایج: 17222  

Journal: :Toxicology and applied pharmacology 1999
R K Zalups D W Barfuss L H Lash

Influences of biliary obstruction and systemic depletion of glutathione (GSH) on the disposition of a low nontoxic iv dose of inorganic mercury were evaluated in rats in the present study. Specifically, the disposition of mercury in the kidneys, liver, small and large intestines, and blood was assessed 1 h after the injection of 0.5 micromol/kg mercuric chloride in control rats and rats pretrea...

2016
Keisuke Gotanda Takeshi Hirota Jumpei Saito Masato Fukae Yu Egashira Noritomo Izumi Mariko Deguchi Miyuki Kimura Shunji Matsuki Shin Irie Ichiro Ieiri

A variant in the breast cancer resistance protein (BCRP) gene, 421C> A is a useful biomarker for describing large inter-individual differences in the pharmacokinetics of sulfasalazine (SASP), a BCRP substrate. However, large intra-genotypic variability still exists in spite of the incorporation of this variant into the pharmacokinetics of SASP. Since miR-328 negatively regulates BCRP expression...

Journal: :The Boston Medical and Surgical Journal 1902

Journal: :Netherlands Journal of Agricultural Science 1972

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