نتایج جستجو برای: intra nasal delivery
تعداد نتایج: 343277 فیلتر نتایج به سال:
background : upper endoscopy, as an important diagnostic and occasional therapeutic tool is invasive. sedation of patients during the endoscopy procedure with minimal side effects could raise patient tolerability, allowing for ease and increased effectiveness of this procedure. materials and methods: in this study, 105 patients who were candidates for the upper endoscopy procedure were randomly...
purpose: to report the clinical and histopathological features of recurrent atypical fibrous histiocytoma of the corneo-scleral limbus followed by intra-epithelial squamous neoplasia. case report: a 25-year-old female patient presented with a recurrent vascularized gelatinous mass in the left nasal limbus. the preliminary histopathological diagnosis of the previously excised lesion was an amela...
one of the applications of nanotechnology is use of carbon nanotubes for the targeted delivery of drug molecules. to demonstrate the physical and chemical properties of biomolecules and identify new material of drug properties, the interaction of carbon nanotubes (cnts) with biomolecules is a subject of many investigations. cnts is a synthetic compound with extraordinary mechanical, thermal, el...
The aim of this paper is the preparation and characterization of drug delivery systems for a potential brain delivery by intranasal administration. It is possible to reach the central nervous system with alternative routes through which therapeutic agents can bypass the blood brain barrier: that is the nasal administration. Intranasal drug administration is non-invasive and it could be a promis...
BACKGROUND Despite the prevalence of rhinosinusitis that affects 10%-15% of the population, current inhalation therapy shows limited efficacy. Standard devices deliver <5% of the drugs to the sinuses due to the complexity of nose structure, secluded location of the sinus, poor ventilation, and lack of control of particle motions inside the nasal cavity. METHODS An electric-guided delivery sys...
OBJECTIVES The purpose of this study was to directly compare the pharmacokinetic (PK) profile of 22-mg sumatriptan powder delivered intranasally with a novel Breath Powered™ device (11 mg in each nostril) vs a 20-mg sumatriptan liquid nasal spray, a 100-mg oral tablet, and a 6-mg subcutaneous injection. BACKGROUND A prior PK study found that low doses of sumatriptan powder delivered intranasa...
Background: Respiratory distress syndrome (RDS) is a major cause of mortality among premature neonates. The present study was conducted to find out whether early nasal CPAP therapy could eliminate the need for mechanical ventilation in premature neonates with RDS. Materials and methods: For this clinical trial, premature neonates with RDS during the first 6 hours following the delivery were as...
OBJECTIVE To determine effects of probiotic consumption on clinical and immunological parameters of seasonal allergic rhinitis (SAR) in an out-of-season single nasal allergen challenge. METHODS In a study registered at ClinicalTrials.Gov (NCT01123252), a 16-week dietary intervention was undertaken in 60 patients with allergic rhinitis (>16 years old). Using a double-blinded, placebo-controlle...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید