introduction: epilepsy is one of the most common neurological disorders. in spite of the fact that a great development has been made regarding therapy against epilepsy, little is known, however, about the precise mechanism of the epilepsy. pentylenetetrazol (ptz) is one of the most often used epileptogenic agents. hence the main purpose of the present work was to determine the effect of ptz as ...

introduction: pentylenetetrazol (ptz) is one of the most often used epileptogenic agents. several effects of this epileptogenic drug have been described, but the mechanism of the epileptogenic action of ptz at the cellular level is still unclear. in this study the effect of ptz, on the ionic currents of d5 neuronal soma membrane in helixaspersa, using intracellular recording technique was inves...

It has been suggested that changes in intracellular calcium mediate the induction of a number of important forms of synaptic plasticity (e.g., homosynaptic facilitation). These hypotheses can be tested by simultaneously monitoring changes in intracellular calcium and alterations in synaptic efficacy. We demonstrate how this can be accomplished by combining calcium imaging with intracellular rec...

The traditional theory holds that the information transmission between nerve cells includes electrical and chemical transmission; however, these known functional features do face some difficulties to explain fast efficient processing cognitive processes in brain due existing limitations of neuronal networks, such as dendritic axonal propagation delays well synaptic time delay have been debated ...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: ischemic heart diseases are the most common cardiovascular diseases. this study aimed to assess the effects of video training about risk factors based on health belief model on knowledge and attitude of myocardial infarction patients after discharge. methods: this was a quasi-experimental study conducted in 201...

PURPOSE A cortically generated Lennox-Gastaut type seizure is associated with spike-wave/poly-spike-wave discharges at 1.0-2.5 Hz and fast runs at 7-16 Hz. Here we studied the patterns of synchronization during runs of paroxysmal fast spikes. METHODS Electrographic activities were recorded using multisite intracellular and field potential recordings in vivo from cats anesthetized with ketamin...

abstractin the present work we set out to investigate the neuroprotective effects of noscapine (0.5-2 µm) in presence of d-glucose on primary murine foetal cortical neurons after oxygen–glucose deprivation/24 hrs recovery. cell viability, nitric oxide production and intracellular calcium ([ca2+]i) levels were evaluated by mtt assay, the modified griess method and fura-2 respectively. 25 and 100...

l-asparaginase has remarkable properties which make it useful in dual pharmaceutical and food industries.in this study, simple and advantageous method has been validated for rapid and precise determination of intracellular l-asparaginasein bacterial species. a suspension of bacterial cells was used instead ofcell extract and incubated by substrate (asparagine) after simple wash and centrifugati...