نتایج جستجو برای: intrahepatic cholestasis of pregnancy

تعداد نتایج: 21189888  

2014
Victoria Geenes Anita Lövgren-Sandblom Lisbet Benthin Dominic Lawrance Jenny Chambers Vinita Gurung Jim Thornton Lucy Chappell Erum Khan Peter Dixon Hanns-Ulrich Marschall Catherine Williamson

Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific liver disorder associated with an increased risk of adverse fetal outcomes. It is characterised by raised maternal serum bile acids, which are believed to cause the adverse outcomes. ICP is commonly treated with ursodeoxycholic acid (UDCA). This study aimed to determine the fetal and maternal bile acid profiles in normal and IC...

2013
Shadi Abu-Hayyeh Georgia Papacleovoulou Anita Lövgren-Sandblom Mehreen Tahir Olayiwola Oduwole Nurul Akmal Jamaludin Sabiha Ravat Vanya Nikolova Jenny Chambers Clare Selden Myrddin Rees Hanns-Ulrich Marschall Malcolm G Parker Catherine Williamson

UNLABELLED Intrahepatic cholestasis of pregnancy (ICP) is the most prevalent pregnancy-specific liver disease and is associated with an increased risk of adverse fetal outcomes, including preterm labor and intrauterine death. The endocrine signals that cause cholestasis are not known but 3α-sulfated progesterone metabolites have been shown to be elevated in ICP, leading us to study the impact o...

Journal: :Journal of hepatology 2000
F Lammert H U Marschall A Glantz S Matern

Frank Lammert, Hanns-Ulrich Marschall1, Anna Glantz2 and Siegfried Matern Department of Internal Medicine III, Aachen University of Technology – RWTH, Aachen, Germany, 1Karolinska Institutet, Department of Medicine, Division of Gastroenterology and Hepatology, Huddinge University Hospital, Stockholm, and 2Department of Obstetrics and Gynecology, Sahlgren’s University Hospital, East, Göteborg, S...

Journal: :Reproductive health of woman 2022

The article is devoted to the most common liver disease which associated with pregnancy – obstetric cholestasis. frequency of this pathology among all disorders in pregnant women almost 27%, second only viral hepatitis. On average, it diagnosed 2–4 cases per 1000 pregnancies. A characteristic feature cholestasis tendency recurrent course future pregnancies, observed 60–70% next This disorder us...

Journal: :International Journal of Reproduction, Contraception, Obstetrics and Gynecology 2020

Journal: :Human molecular genetics 2000
P H Dixon N Weerasekera K J Linton O Donaldson J Chambers E Egginton J Weaver C Nelson-Piercy M de Swiet G Warnes E Elias C F Higgins D G Johnston M I McCarthy C Williamson

Intrahepatic cholestasis of pregnancy (ICP) is a liver disease of pregnancy with serious consequences for the mother and fetus. Two pedigrees have been reported with ICP in the mothers of children with a subtype of autosomal recessive progressive familial intrahepatic cholestasis (PFIC) with raised serum gamma-glutamyl transpeptidase (gamma-GT). Affected children have homozygous mutations in th...

2010
Bita Behnava Seyed Moayed Alavian

A middle-aged woman suffering from jaundice and pruritus that had begun a month previously was presented to a physician.At the first assessment, laboratory findings had revealed a cholestatic pattern and serologic tests for hepatitis B virus (HBV), hepatitis C virus (HCV) and hepatitis A virus (HAV) were negative. Normal findings of abdominal computed tomography (CT) scan and endoscopic retrogr...

Journal: :The Yale Journal of Biology and Medicine 1979
Caroline A. Riely

Familial intrahepatic cholestasis is a confusing group of syndromes. Four forms are defined and discussed in detail ("arteriohepatic dysplasia," the Byler syndrome, the THCA syndrome, and Norwegian cholestasis). A comparison of the distinguishing characteristics of these syndromes demonstrates that they share many features, including areflexia, retinal degeneration, and paucity of the intrahepa...

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