An 18-month-old Standardbred filly had a large intraocular tumor involving the optic nerve. The tumor was a malignant medulloepithelioma, a rare intraocular neoplasm derived from the primitive medullary epithelium. By light microscopy the tumor had cords and lobules of primitive neuroepithelial cells that formed clefts and true rosettes. Electron microscopy of the rosettes showed a girdle of zo...

The short-term effects on aqueous humor flow dynamics of single doses of acetazolamide and L-epinephrine, alone and combined, were studied in selected young, normal men. Analysis of aqueous flow before and after medication was facilitated, by graphic representation of flow versus intraocular pressure, the flow curve. Acetazolamide reduced intraocular pressure and Pk of Goldmann without affectin...

Intraocular surgical procedures in general and filtering surgery in particular, predispose to cataract formation or accelerate pre-existing lens opacification thus the management of a visually significant cataract in a glaucoma patient who has had a previous trabeculectomy is a common clinical challenge, with the possibility that the intraocular surgery might result in filtration failure and lo...

An attempt was made to study the associations between age, intraocular pressure, and systolic blood pressure. The eyes of 90 non-glaucomatous, ocular normotensive patients and of 142 ocular hypertensive patients were examined. A third group was formed from these two by stratification, to mirror the intraocular pressure distribution in the general population. In all three groups systolic blood p...

PURPOSE To develop a method for measurement of intraocular pressure in conscious, unsedated rats. METHODS. The animal was gently held with a thick fabric mitten, topical anesthetic drops were instilled and the Tono-Pen was applied to the cornea. RESULT Measurements in a total of 51 animals did not differ significantly among four strains studied: the overall mean intraocular pressure+/-standar...

Both intraocular pressure and aqueous humour turnover rate were determined at intervals over three months in three females in order to investigate whether a correlation existed between these variables and the menstrual cycle. Not only was there a lack of correlation between intraocular pressure or aqueous humour flow rate and menses but intraocular pressure and aqueous humour flow rate were als...

An attempt was made to study the associations between age, intraocular pressure, and systolic blood pressure. The eyes of 90 non-glaucomatous, ocular normotensive patients and of 142 ocular hypertensive patients were examined. A third group was formed from these two by stratification, to mirror the intraocular pressure distribution in the general population. In all three groups systolic blood p...

The use of sodium hyaluronate in cataract surgery and intraocular lens implantation is often followed by a postoperative rise of intraocular pressure. A trial is described in which 10 patients underwent bilateral cataract extraction and Binkhorst intraocular lens implantation with the use of sodium hyaluronate. The enzyme hyaluronidase was instilled into the anterior chamber of the right eye on...

We examined 241 leprosy patients and 135 age-matched healthy controls in central South Korea, measuring intraocular pressure in the supine and the upright positions and measuring the size of the pupils in darkness as an indication of ocular autonomic dysfunction. The mean intraocular pressure was significantly lower in the patients and the mean size of pupils was significantly smaller in the pa...

The effect of atracurium on intraocular pressure was studied by comparing it with pancuronium in a randomised controlled trial. The intraocular pressure was measured in patients undergoing cataract surgery before administration of the muscle relaxant, at 1, 3, and 5 minutes after its administration, and at 1 minute after tracheal intubation. Atracurium was found to decrease intraocular pressure...