background: our information regarding immunity to toxoplasmosis among reproductive age women is indeterminate and there is significant variation between reported results; it is necessary to perform a meta-analysis study on subjects to obtain required findings and develop preventive measures accordingly. objective: estimation level of immunity to toxoplasmosis in reproductive ages. materials and...

conclusions more than 95% of 15 to 25 year-old women (main reproductive age in iran) are within acceptable immunity range. level of immunity to rubella in women of reproductive age in this region appears satisfactory. patients and methods this descriptive cross-sectional study was conducted on 760 women younger than 25 years attending medical centers in ahvaz. a sample of 3 ml of venous blood w...

background: the aim of the present study was the comparison of humoral and cell-mediated immunity in broilers fed with different levels of zinc during a coccidiosis challenge. methods: one hundred and forty- four one-day-old broiler chicks were used with three dietary zinc (40, 120 and 200 mg/kg). at 14 d of age, all birds were inoculated orally with 5×10 3 sporulated oocysts of e. tenella . at...

humoral immune response of vaccine-i (supermatent from sonicated sporulated oocyst), vaccine –ii (sediment from sonicated sporulated oocyst) and vaccine –iii (un-sonicated sporulated oocyst) against conccidiosis in chickens was determined by indirect haemagglutination (iha) test. iha antibody titre was significantly higher (p

Merkel Cell Carcinoma (MCC) is a rare, but highly aggressive cancer of the skin. In MCC patients, inhibitors targeting programmed cell death-1 (PD-1) immune checkpoint pathway have yielded remarkable antitumor activity by stimulating cancer-specific T-cell immunity. Here, we identify previously unknown role for PD-1 as growth-promoting receptor intrinsic to cells. four established human lines, ...

Aims: Programmed cell death ligand 1 (PD-L1) is the of programmed (PD-1), which a host immunity inhibitory receptor. Expression PD-L1 in diverse tumor types has been widely discussed, while there little research about intrinsic-PD-1. Phospho-S6 (p-S6) an important downstream effector PI3K/AKT/mTOR pathway. Our study was focused on investigating expression cancer cell-intrinsic PD-1, and p-S6 pr...

Deficiences imunitaire acquises Les , deficits nnmumtaires pathologiques af­ systeme des phagocytes, l'immunite a mechation_ cellulare :t la synthese des im­ Illfnoglobulmes so1t separement, soit con­Jom temen t. La manifestation .clinique de ces deficits est la ,frequence _des mfections bacterielles, vir­ales et mycotiques.  Le triteJent s deficits immunitaire a part la therap1e antnnfectieu...