Cervical vagus nerve stimulation is in a great variety of clinical situations indicated as form treatment. It textbook knowledge that at the cervical level contains many different fiber classes. Yet, recently, several reports have shown this also may contain an additional class potentially noradrenergic fibers, suggested to denote efferent sympathetic fibers. As such, nature and presence these ...

Leprosy neuropathy is characterized by initial involvement of the small nerve fibers, later followed by involvement of the large fibers, when routine nerve conduction studies become abnormal. To increase the diagnostic yield and precocity of these studies, we applied the near nerve technique to the sural nerve of 8 leprosy patients. Contrary to our expectations, the main component of the sural ...

Using a double labeling indirect immunofluorescent technique, we studied the guinea pig trigeminal ganglion and eye for co-localization of substance P and calcitonin gene-related peptide. In the trigeminal ganglion, the number of neurons immunoreactive for calcitonin gene-related peptide significantly outnumber those immunoreactive for substance P, but virtually all substance P positive neurons...

A close contact between melanocytes and nerve fibers in the epidermis has been demonstrated in normal human skin. The interactions between the neural and immune systems play an important role in the pathophysiology of certain dermatoses. In this study, we investigated the intraepidermal nerve fibers and their contacts with melanocytes in the lesions of melasma using double labeled immunofluores...

The frequency selectivity of the P, NP I, and NP II channels of the four-channel model of mechanoreception for glabrous skin was measured psychophysically by an adaptation tuning curve procedure. The results substantially extend the frequency range over which the frequency selectivity of these channels is known and further confirm the hypothesis that the input stage of each of these channels co...

background: considering the common origin of skin and peripheral nervous system, a tube of dermal layer of skin hypothetically can be an ideal conduit for nerve reconstruction. an experimental study performed to evaluate the nerve regeneration of efficacy into a dermal tube. methods: sixty male wistar rats were used. a 10 mm gap was produced in right sciatic nerves. in group a the autogenous ne...

this paper presents a new three-dimensional curvelet transform based dictionary learning for automatic segmentation of intraretinalcysts, most relevant prognostic biomarker in neovascular age-related macular degeneration, from 3d spectral-domain optical coherencetomography (sd-oct) images. in particular, we focus on the spectralis sd-oct (heidelberg engineering, heidelberg, germany) system, and...

Orexin/hypocretin-containing neurons in lateral hypothalamus (LH) are implicated in the neurobiology of nicotine addiction. However, the neuroanatomical relationships between orexin-neurons/nerve fibers and nicotine-activated cells within the reward-addiction neurocircuitry is not known. In the present study in mice, we first used c-Fos immunohistochemistry to identify CNS cells stimulated by a...

A new nerve fiber model has been developed, incorporating electrical characteristics of human myelinated sensory nerve fibers. It will be used to determine the response of myelinated somatosensory nerve fibers in the spinal cord to electrical stimulation with an epidurally placed electrode. Index terms Spinal cord stimulation, human sensory nerve fiber, simulated action potential, chronaxie dia...

Objective- The objective was to assess local effect of brain derived neurotrophic factor (BDNF) on functional recovery of peripheral nerve in rat sciatic nerve transection model. Design- Experimental study. Animals- Sixty male healthy white Wistar rats Procedures- The animalswere randomized into four experimental groups of 15 animals each: In sham-operated group (SHAM), sciatic nerve was exp...