Amyloidosis, an infiltrative disease characterized by deposition of high molecular weight insoluble protein has a low detection rate and poor prognosis with congestive heart failure being the most common cause of death. Although definitive diagnosis is based on endomyocardial biopsy, this is rarely performed due to procedural risk and sampling error. Traditional non-invasive imaging, such as tr...

oninvasive imaging of the coronary arteries is fraught with reat difficulties: Most obviously, coronary vessels have mall dimensions, which requires high spatial resolution. lso, they are subjected to rapid motion because of cardiac ontraction. Sufficient temporal resolution is thus necessary o avoid artifacts. Finally, in invasive angiography, the oronary artery lumen can be selectively filled...

Non-invasive coronary imaging has recently seen a rapid expansion of interest, fuelled largely by technical advances in both computed tomography (CT) and cardiac magnetic resonance imaging (CMR). The race is on for these two modalities to provide routine and robust imaging of coronary arteries in clinical practice. The rate of this progress has inevitably provided a bewildering array of develop...

First-pass perfusion cardiac magnetic resonance (FPP-CMR) is becoming an essential non-invasive imaging method for detecting deficits of myocardial blood flow, allowing the assessment coronary heart disease. Nevertheless, acquisitions suffer from relatively low spatial resolution and limited coverage. Compressed sensing (CS) methods have been proposed to accelerate FPP-CMR achieve higher resolu...

Approximately 100 million people undergo noncardiac surgery annually worldwide. It is estimated that around 3% of patients undergoing noncardiac surgery experience a major adverse cardiac event. Although cardiac events, like myocardial infarction, are major cause of perioperative morbidity or mortality, its true incidence is difficult to assess. The risk of perioperative cardiac complications d...

Diabetic cardiomyopathy is a distinct myocardial complication of the catabolic state of untreated insulin-dependent diabetes mellitus in the streptozotocin-induced diabetic rat. Exercise training has long been utilized as an effective adjunct to pharmacotherapy in the management of the diabetic heart. However, the in vivo functional benefit(s) of the training programs on cardiac cycle events in...

   18F-FDG is the most commonly used radioisotope in PET scanning and is administered intravenously. When patients cannot cannulated, there are limited options available for functional tumour assessment. A fifty year old male presented for investigation of a suspected lung carcinoma identified during investigation of pneumonia. The patient had a severe needle phobia, intellectual dis...

Over the past decade, rapid advances in imaging technologies have enabled state-of-the-art image-based analysis of cardiac function at a variety of scales and from multiple aspects, such as cardiac electrophysiology, cardiac biomechanics, and cardiovascular system. This special issue aims to showcase developments in cardiac image computing over the past five years, with a special emphasis given...

Despite advances in the pharmacologic and interventional treatment of coronary artery disease (CAD), atherosclerosis remains the leading cause of death in Western societies. X-ray coronary angiography has been the modality of choice for diagnosing the presence and extent of CAD. However, this technique is invasive and provides limited information on the composition of atherosclerotic plaque. Co...

parathyroid adenomas, or hyperplasia may be present in patients with hypercalcemia. treatment is by surgical excision, but about 10% of the lesions may be in ectopic locations. pre-operative localization of the lesions with non-lvasive imaging, using radionuclides, ultrasound, ct, or mr], may simplify surgery, and reduce patient morbidity. however, the reports of the accuracy of the currently a...