many studies suggested that fractals could be brought in any structural anarchy, such as cancers, for diagnosis and prognosis evaluation by quantifying it and expressing it in terms of fractal geometry. in this study, we aimed to evaluate pathologic grades or breast carcinomas by fractal analysis. this cross-sectional study was performed on 60 women with breast ductal carcinoma. from all the pa...

The study was done over a period of 10 years, 1996-2005 and it included 562 mammary cancer patients. Of the 562 cases, 100 cases of invasive mammary carcinoma included in this study were investigated from an immunohistochemical point of view. The p53 overexpression was more frequently seen in patients under 50 (23 cases, that is 54.76%), compared to those over 50 years old (19 cases, that is 45...

Abstract Hyperechogenic breast lesions are a relatively rare finding at ultrasonography and traditionally thought to be benign. However, hyperechogenicity on the ultrasound alone does not provide enough evidence rule out malignancy completely. We herein reported short series of nine cases echogenic malignant lesions, which include invasive ductal carcinoma, carcinoma in situ, lobular angiosarco...

OBJECTIVE To correlate the different non masslike enhancement categories detected by Magnetic Resonance Imaging (MRI) and the corresponding histological findings. PATIENTS AND METHODS Two experienced radiologists reviewed the MRI examinations of 94 patients presenting non mass-like enhancements who had performed histological evaluation. According to the BI-RADS (Breast Imaging Reporting and D...

We report a case of axillary metaplastic breast carcinoma (MBC) with triple negative (ER-/PR-/Her2-) phenotype, concurrent with multifocal invasive ductal carcinoma (IDC) of ipsilateral pectoral breast (ER+/PR+/Her2-) in a 60-year-old woman. The two tumors demonstrate different morphology, immunophenotype, and opposite response to neoadjuvant chemotherapy of paclitaxol, adriamycin, and cyclopho...

tinct histologic type of invasive carcinoma that was first described by Page et al. in 1983 (1) and is characterized by a cribriform histologic pattern in the majority of its invasive component (1). Cribriform carcinoma is a welldifferentiated variant of invasive ductal carcinoma and has a relatively favorable prognosis and low frequency of axillary nodal metastases (2). To our knowledge, the r...

Granular cell tumor is a rare benign non-encapsulated tumor that mostly presents in oral cavity. Breast localization is uncommon and occurs in about one per 1000 cases of breast cancers. It mainly affects premenopausal women showing the possible role of estrogen and progesterone levels in the progression of this tumor. Granular cell tumor is a great emulator of the invasive ductal carcinoma of ...

Introduction: Breast cancer is the most common cause of Cancer-related death among women. The aim of this study was to assess the pathologic findings of patients with breast cancer who were referred to the pathology ward in Bandarabbas during 2002 to 2010. Methods and Materials: In this descriptive study in 2010, all patients with breast cancer who were referred to the pathology ward of Banda...

OBJECTIVE To evaluate invasion criteria in fine needle aspiration cytology (FNAC) of histologically diagnosed breast ductal carcinoma in situ (DCIS) and invasive carcinoma and to evaluate their usefulness in identifying an invasive component in addition to DCIS. STUDY DESIGN The material consisted of 331 smears diagnosed as suspicious for or consistent with DCIS and in which histology had sho...

BACKGROUND Protein kinase D1 is downregulated in its expression in invasive ductal carcinoma of the breast and in invasive breast cancer cells, but its functions in normal breast epithelial cells is largely unknown. The epithelial phenotype is maintained by cell-cell junctions formed by E-cadherin. In cancer cells loss of E-cadherin expression contributes to an invasive phenotype. This can be m...