Three sensitive, selective, rapid and easily reproducible spectrophotometric methods (A-C) have been developed for the determination of propranolol hydrochloride (PPH) as a hydrochloride free base propranolol (PPL) in bulk sample and in its dosage forms. These methods are based on ion-pair formation between propranolol as a hydrochloride and free base and three acidic (sulphonphthalein) dyes; n...

A review of heteroditopic interlocked molecules and their application as receptors for simple inorganic ion pair species. The details the design recognition properties rotaxane catenane receptors, well highlighting some experimental challenges; hence, it provides insight into possible future avenues research in this youthful field.

Ion-pairing is reported to improve the lipophilicity and subsequently the transport rate of polar drugs across lipid membranes. Lipophilisation of ionic drugs with high aqueous solubilities by ion-pair formation with appropriate counter-ion have proven to be promising for several applications. The aim of this review is to present the usefulness of ion-pair for improving the poor bioavailability...