objective: the aim of the present study is assessment of insulin resistance (ir) in obese women by tyg-index and compared with the homa-ir index. materials and methods: this cross-sectional study was performed on 61 obese women aged 18-45 years. weights, height, waist circumference (wc) were measured and body mass index (bmi) was calculated and recorded. a sample of fasting serum was collected ...

TGF/Smad3 promotes renal fibrosis, but the mechanisms that regulate profibrotic genes remain unclear. We hypothesized that miR-192, a microRNA expressed in the kidney may mediate renal fibrosis in a Smad3-dependent manner. Microarray and real-time PCR demonstrated a tight association between upregulation of miR-192 in the fibrotic kidney and activation of TGF/Smad signaling. Deletion of Smad7 p...

Effective drug delivery systems require controlled drug release at the target cancer cell. While strategies for targeting tumors have been extensively studied, a better understanding of the necessary technology for controlling the spatiotemporal release of a drug is still needed. It has been established that the use of light can be a unique tool for controlling drug release. While UV light can ...

The application of IR 786 perchlorate (IR-786) as a selective optical sensor for cyanide anion in both organic solution (acetonitrile (MeCN), 100%) and solvent-free solid surfaces was demonstrated. In MeCN, IR-786 was selective to two anions in the following order: CN(-) > OH(-). A significant change in the characteristic dark green color of IR-786 in MeCN to yellow was observed as a result of ...

Preprocessing To prepare the images for the network, each of the training images was resized to 192 pixels by 192 pixels. To create additional training images, each of the training images was elastically distorted. For each of the original training images, four randomly generated elastic distorted images were generated and then resized down to 192 by 192 pixels. In addition, each training image...