Abstract Background Obesity is a health problem defined by surplus body fat accumulation and one of the leading causes morbidity mortality. Earlier studies indicated influence brain-derived neurotrophic factor ( BDNF ) molecular alterations in development obesity. One these variations G196A single nucleotide polymorphism (Val66Met; SNP rs6265), which impairs intracellular trafficking reduces se...

background: a high-fat diet (hfd) and fat accumulation promote the oxidative stress formation, which in turn has hazardous effects on reproductive system and fertility. therefore, the present study examines the potential positive effects of a restricted high-fat diet (rhfd) and antioxidants consumption on sperm parameters in rats. methods: 48 male albino wistar rats divided to four groups (n=12...

BACKGROUND: The acute phase response is beneficial to theanimal in restoring homeostasis, and measuring the circulatingacute phase proteins, cytokines, and enzymes can be used toevaluate the innate immune system's responses to invader agentssuch as bacterial lipopolysaccharide. Measurement of theseparameters has shown to be useful as diagnostic and prognosticmarkers in animal endotoxemia. OBJEC...

Multidrug resistance (MDR) is a main cause of failure in the chemotherapeutic treatment of malignant disorders. One of the well-known genes responsible for drug resistance encodes the multidrug resistance- associated protein (MRP1). The association of MRP1 with clinical drug resistance has not systematically been investigated in Iranian pediatric leukemia patients. We therefore applied real-tim...

background: physical exercises can influence some anthropometric and fitness components differently. the aim of present study was to evaluate how a relatively long‑term training program in 11‑14‑year‑old male iranian students affects their anthropometric and motor performance measures. methods: measurements were conducted on the anthropometric and fitness components of participants (n = 28) pri...

conclusions this study demonstrated that rt and at are equally effective in reducing hepatic fat content and liver enzyme levels among patients with nafld. however, aerobic exercise specifically improves nafld independent of any change in body weight. results after training, hepatic fat content was markedly reduced, to a similar extent, in both the aerobic and resistance exercise training group...

The major difference between Iranian traditional medicine and allopathic medicine is in the application  of  evidence  and  documents.  In  this  study,  criteria  for  evidence-based  practice  in  Iranian traditional medicine and its rules of practice were studied. The experts' views were investigated through in- depth, semi-structured interviews and the results were categorized into four mai...

URINARY INCONTINENCE MANAGEMENT: A SYSTEMATIC REVIEW AND META-ANALYSIS Sakineh Hajebrahimi, Alireza Mahboub-Ahari, Neda Kabiri, Fariba Pashazadeh. Department of Urology, Iranian Evidence-Based Medicine Center of Excellence(RCEBM), Tabriz University of Medical Sciences, Tabriz, Iran; Iranian Center of Excellence in Health Management, Tabriz University of Medical Sciences, Tabriz, Iran; Ph.D. Stu...

Journal of Research in Medical Sciences | May 2014 | 385 Observation of constant increase of self-citation rate by Iranian scholars in all fi elds shows that self-citation plays an important role in scientifi c communication even in the fi eld of medicine. Base on Ghane’s study[8] the rate of journal self-citation among Iranian medical journals is about 61.5% and with reared to the Iranian auth...