objective: iron deficiency anemia is among the most common types of childhood anemia. according to the world health organization, approximately 5 billion people were suffering from iron deficiency anemia worldwide in 2001. aside from causing anemia, iron deficiency can negatively affect the physical and mental development of children and adolescents. several studies have discussed the consequen...

The prevalence of anemia in pregnancy varies considerably because of the differences in social conditions, lifestyles, and health seeking behaviors across different cultures. Anemia affects all pregnant women in the world—52 % in developing countries compared with 23 % in the developed world. It is one of the most prevalent nutritional deficiency problems affecting pregnant females. Iron defici...

Iron-refractory iron-deficiency anemia (IRIDA) is an autosomal recessive disorder caused by mutations in TMPRSS6. Patients have hypochromic microcytic anemia refractory to oral iron and are only partially responsive to parenteral iron administration. We report a French-Canadian kindred in which 2 siblings presented in early childhood with severe microcytic anemia, hypoferremia, and hyperferriti...

Acute phase proteins play a significant role in anemia of chronic disease and thought to be beneficial in maintain homeostasis. In both the condition, anemia of chronic disease as well as iron deficiency anemia alteration in iron homeostasis takes place. The study includes patients of pulmonary tuberculosis patients (ACD), Iron deficiency anemia (IDA) patients and control subjects. Serum CRP, S...

Iron deficiency is a manifestation of celiac disease (CD) usually attributed to a decreased absorptive surface, although no data on the regulation of iron transport under these conditions are currently available. Our aim was to evaluate divalent metal transporter 1 (DMT1), duodenal cytochrome b (Dcytb), ferroportin 1 (FP1), hephaestin, and transferrin receptor 1 (TfR1) expression, as well as ir...

background recent studies suggest an association between h. pylori infection and disorders such as iron deficiency anemia and growth delay. considering the high prevalence of h. pylori infection and iron deficiency anemia, this study was performed in order to evaluate their relevance in children undergoing an upper endoscopy. materials and methods in this case-control study, children aged 2 to ...

BACKGROUND Diagnosis and treatment of iron deficiency anemia in older subjects improves their quality of life. Serum ferritin as a marker of iron stores is an acute phase protein. In older subjects who usually have many concomitant chronic medical conditions, serum ferritin may increase in response to inflammatory processes irrespective of iron stores. This study was performed to determine the ...

INTRODUCTION Thrombocytosis is a common disorder in patients diagnosed with iron deficiency anemia. The decreased platelet counts commonly found iron deficiency anemia is rarely reported in clinical practice. The exact mechanism of the occurrence of thrombocytopenia in iron deficiency anemia remains unclear. In this case report we discuss a triad of symptoms seen in the African American populat...

c i e b Since the association between gluten intake and celiac disease (CD) was established by Dicke1 during World War II, our understanding of the pathophysiology of gluten-sensitive enteropathy has markedly increased, especially with the resources of molecular research. However, although it is clear that gluten intake causes enteropathy and extraintestinal disease in genetically-susceptible i...