نتایج جستجو برای: irreversible expansion
تعداد نتایج: 165010 فیلتر نتایج به سال:
We consider the quantum evolution of classically chaotic systems in contact with surroundings. Based on h̄-scaling of an equation for time evolution of the Wigner’s quasiprobability distribution function in presence of dissipation and thermal diffusion we derive a semiclassical equation for quantum fluctuations. This identifies an early regime of evolution dominated by fluctuations in the curvat...
OBJECTIVES We aimed to characterize the tissue changes within the perfusion bed of infarct-related vessels in patients with acutely reperfused myocardial infarction (MI) using cardiovascular magnetic resonance (CMR). BACKGROUND Even in successful early revascularization, intermittent coronary artery occlusion affects the entire perfusion bed, also referred to as the area at risk. The extent o...
We report the discovery of giant magnetostriction and huge negative thermal expansion (NTE) in itinerant-electron metamagnetic compound La0.85Ce0.15Fe12B6. This system presents multiple magnetic transformations, antiferromagnetic–ferromagnetic (AFM–FM) ferromagnetic–paramagnetic (FM–PM), driven by changes both external field temperature. The magnetic-field–dependent exhibits irreversible abrupt...
Liver disease, particularly alcoholic cirrhosis, is associated with a number of interesting chemical changes which result in structural and metabolic abnormalities of the erythrocyte membrane leading to microscopically observable cell shape changes and hemolytic anemia varying from very mild to potentially lethal. Increase in unesterified serum cholesterol owing to lecithin cholesterol acyl tra...
Non-small cell lung cancer (NSCLC) driven by activating mutations in epidermal growth factor receptor (EGFR) constitutes up to 10% of NSCLC cases. According to the NCCN recommendations, all patients (with the exception of smoking patients with squamous cell lung cancer) should be screened for the presence of activating EGFR mutations, i.e. deletion in exon 19 or point mutation L858R in exon 21,...
The Fe-Cr-Ni stainless steels are well known for their ductile behaviour at cryogenic temperatures. This implies development and evolution of plastic strain fields in the stainless steel components subjected to thermo-mechanical loads at low temperatures. The evolution of plastic strain fields is usually associated with two phenomena: ductile damage and strain induced martensitic transformation...
The most primitive engrafting hematopoietic stem cell has been assumed to have a fixed phenotype, with changes in engraftment and renewal potential occurring in a stepwise irreversible fashion linked with differentiation. Recent work shows that in vitro cytokine stimulation of murine marrow cells induces cell cycle transit of primitive stem cells, taking 40 h for progression from G0 to mitosis ...
BACKGROUND AND PURPOSE Patient selection for acute stroke therapy based on physiology rather than on time may lead to expansion of the therapeutic window, improved outcomes, and fewer side effects than currently achieved. This approach requires early determination of both irreversible (core) and reversible (penumbra) ischemia in acute stroke. METHODS Using established perfusion thresholds, we...
Chronic lymphocytic leukemia (CLL) is characterized by constitutive activation of the B-cell receptor (BCR) signaling pathway, but variable responsiveness of the BCR to antigen ligation. Bruton's tyrosine kinase (BTK) shows constitutive activity in CLL and is the target of irreversible inhibition by ibrutinib, an orally bioavailable kinase inhibitor that has shown outstanding activity in CLL. E...
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