نتایج جستجو برای: ischemic postconditioning

تعداد نتایج: 85574  

Journal: :Genetics and molecular research : GMR 2014
K Ran D-L Yang Y-T Chang K-M Duan Y-W Ou H-P Wang Z-J Li

We examined the protective effects of Ginkgo biloba extract (EGb761) postconditioning on myocardial ischemia reperfusion injury in rabbits. Four groups of 8 white rabbits were allocated to: pseudo surgery group: the left coronary was lined without blocking for 160 min after thoracotomy; ischemia and reperfusion group (IR): the left anterior descending coronary artery was blocked for 40 min and ...

2017
Durdane Keskin Ramazan Erkin Unlu Erkan Orhan Gamze Erkilinç Nihal Bogdaycioglu Fatma Meric Yilmaz

BACKGROUND The aim of this study was to investigate the effects of remote ischemic conditioning on ischemia-reperfusion injury in rat muscle flaps histopathologically and biochemically. METHODS Thirty albino rats were divided into 5 groups. No procedure was performed in the rats in group 1, and only blood samples were taken. A gracilis muscle flap was elevated in all the other groups. Microcl...

Journal: :American journal of physiology. Heart and circulatory physiology 2006
Nicolas Couvreur Laurence Lucats Renaud Tissier Alain Bize Alain Berdeaux Bijan Ghaleh

Postconditioning, i.e., brief intermittent episodes of myocardial ischemia-reperfusion performed at the onset of reperfusion, reduces infarct size after prolonged ischemia. Our goal was to determine whether postconditioning is protective against myocardial stunning. Accordingly, conscious chronically instrumented dogs (sonomicrometry, coronary balloon occluder) were subjected to a control seque...

2016
Yujie Liu Nana Liu Xudong Wang Lei Zhang Min Ren Jiawei Tian

Edaravone, an effective free radical scavenger, can alleviate myocardial ischemia-reperfusion injury (IRI) by decreasing reactive oxygen species (ROS) accumulation. The speckle tracking imaging (STI) could precisely and objectively evaluate the global and regional myocardial deformation. The aim of our study was to assess the protective effect of edaravone postconditioning on IRI in rabbits by ...

2018
Pasquale Pagliaro Saveria Femminò Jasmin Popara Claudia Penna

Mitochondria play a pivotal role in cardioprotection. Here we report some fundamental studies which considered the role of mitochondrial components (connexin 43, mitochondrial KATP channels and mitochondrial permeability transition pore) in postconditioning cardioprotection. We briefly discuss the role of mitochondria, reactive oxygen species and gaseous molecules in postconditioning. Also the ...

2012
Jan Lehotsky Martina Pavlikova Stanislav Straka Maria Kovalska Peter Kaplan Zuzana Tatarkova

Stroke is the second leading cause of death and the primary cause of disability in humans. The phenomenon of ischemic tolerance perfectly describes the quote: “What does not kill you makes you stronger.’’ Ischemic preor postconditioning is actually the strongest known procedure to prevent or reverse delayed neuronal death. It works specifically in sensitive vulnerable neuronal populations, whic...

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