نتایج جستجو برای: isobaric model
تعداد نتایج: 2106299 فیلتر نتایج به سال:
Shotgun proteomic methods involving isobaric tagging of peptides enable high-throughput proteomic analysis. iTRAQ reagents allow simultaneous identification and quantitation of proteins in four different samples using tandem mass spectrometry (MS). In this article, we provide a brief description of proteome analysis using iTRAQ reagents and review the current applications of these reagents in p...
Recent proteomic applications have demonstrated their potential for revealing the molecular mechanisms underlying neurodegeneration. The present study quantifies cerebellar protein changes in mice that are deficient in plasma membrane calcium ATPase 2 (PMCA2), an essential neuronal pump that extrudes calcium from cells and is abundantly expressed in Purkinje neurons. PMCA2-null mice display mot...
Germination of Bacillus anthracis spores involves rehydration of the spore interior and rapid degradation of several of the protective layers, including the spore coat. Here, we examine the temporal changes that occur during B. anthracis spore germination using an isobaric tagging system. Over the course of 17 min from the onset of germination, the levels of at least 19 spore proteins significa...
Inspired by Rearick (1968), we introduce two new operators, LOG and EXP. The LOG operates on generalized Fibonacci polynomials giving generalized Lucas polynomials. The EXP is the inverse of LOG. In particular, LOG takes a convolution product of generalized Fibonacci polynomials to a sum of generalized Lucas polynomials and EXP takes the sum to the convolution product. We use this structure to ...
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