Dear Editor, the recent report on “Isoproterenol infusion in septic shock” is very interesting (1). Wiramus et al. concluded that “use of isoproterenol was associated with an increase of tissue oxygen saturation (1).” In fact, there are some issues of isoproterenol use to be discussed. First, the increased heart rate due to infusion is common (2). On the other hand, the occurrence of paradoxica...

Painful left bundle branch block (LBBB) is characterized by chest pain in setting of transient LBBB, the absence ischemia. Management has focused on pharmacological suppression sinus rate to prevent or invasive therapy with permanent pacing. To determine feasibility using oral theophylline for treatment painful LBBB. N/A A 71-year-old man presented evaluation exertional left-sided that resolved...

We examined, in conscious dogs, the effects of beta-adrenergic stimulation on measurements of left circumflex coronary arterial diameter and blood flow and on calculations of late diastolic coronary resistance (LDCR) and left circumflex coronary internal cross-sectional area (CSA). Isoproterenol (0.1 microgram/kg) initially decreased mean arterial pressure by 25 +/- 2% (mean +/- SEM), and LDCR ...

men. Methods and Results. Responses to two 5-minute intravenous isoproterenol infusions (0.01 ug/kg/min and 0.02 pg/kg/min) were evaluated in six type A and six type B men after pretreatment with either dextrose placebo or atropine (1.2 mg). Atropine significantly potentiated T wave attenuation in the recovery period after isoproterenol infusion (0.30±0.07 mV) compared with placebo (0.54±0.09 m...

The aim of the study was to determine the effect of tetramethylpyrazine phosphate tablets (TPT), a Chinese medicine used for cardiovascular disease, on immunity activity and oxidative injury in rats. Heart failure (HF) was induced by isoproterenol (ISO). After the animal model was established, the rats were administered the TPT by gavage (once a day). The results indicated that TPT improved lef...

the incidence and prevalence of obesity are fast increasing worldwide. various indices have been used to measure and assess obesity. the body mass index (bmi) is the most common and practical of these indices. overweight and obesity exert considerable adverse effects on the cardiovascular system. these effects are mediated through various neurohormonal and cytokine pathways, most of which are i...

objectives: anemia is prevalent in heart failures and is an independent risk factor for adverse clinical outcomes in patients with chf. the aim of the present study was to determine the prevalence of anemia in elderly with systolic heart failure hospitalized in alborz hospital of karaj in 2009. methods & materials: this is a descriptive retrospective study that reviewed 154 medical records of e...

Background: Recently, stem cells have been considered for the treatment of heart diseases, but no marked improvement has been recorded. This is the first study to examine the functional and histological effects of the transplantation of human amniotic mesenchymal stromal cells (hAMSCs) in rats with heart failure (HF). Methods: This study was conducted in the years 2014 and 2015. 35 male Wistar ...