Ca/calmodulin-dependent protein kinases II (CaMKII) have important functions in regulating cardiac excitability and contractility. In the present study, we examined whether CaMKII regulated the transient outward K current (Ito) in whole-cell patch-clamped human atrial myocytes. We found that a specific CaMKII inhibitor, KN-93 (20 mmol/L), but not its inactive analog, KN-92, accelerated the inac...

Indium-tin-oxide (ITO) nanorods (NRs) and nanowhiskers (NWhs) were fabricated by an electron-beam glancing-angle deposition (GLAD) system. These nanomaterials are of interests as transparent conducting electrodes in various devices. Two terahertz (THz) time-domain spectrometers (TDS) with combined spectral coverage from 0.15 to 9.00 THz were used. These allow accurate determination of the optic...

OBJECTIVES The use of indium compounds, especially those of small size, for the production of semiconductors, liquid-crystal panels, etc., has increased recently. However, the role of particle size or the chemical composition of indium compounds in their toxicity and distribution in the body has not been sufficiently investigated. Therefore, the aim of this study was to examine the effects of p...

In the sensorimotor domain, adaptation to distorted sensory input has been well-characterized and is largely attributed to learning mechanisms in the cerebellum that adjust motor output to achieve the same desired sensory outcome. Our interest in the role of the cerebellum in cognitive processes has led us to question whether it also contributes to adaptation in tasks that do not require volunt...

Analog and digital resistive switching characteristics of ITO/CuSCN/Cu ITO/Cu-SPE/Cu memristive devices.

BACKGROUND Although thoracic epidural analgesia (TEA) is considered the gold standard for post-thoracotomy pain relief, thoracic paravertebral block (PVB) and intrathecal opioid (ITO) administration have also been shown to be efficacious. We hypothesized that the combination of PVB and ITO provides analgesia comparable with that of TEA. METHODS After local ethics committee approval, 84 consec...

Indium tin oxide (ITO) films have been deposited onto glass substrates by ifmagnetron sputtering without insitu substrate heating. The as-deposited films have an electrical resistivity of 5x1O a-cm, visible transmittance of about 85%, and infrared (IR) reflectance of above 80% at 5 jim. The effect of sputtering parameters on the deposition rate and the electrical and optical properties of ITO f...

We demonstrate the improved device performances by using structure of poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) film coated onto indium tin oxide (ITO) anodic electrode annealed at 400 °C under normal ambient. The ITO thin films show quality with decreased dislocation density and lattice strain as annealing temperature increases. spin-coated PEDOT:PSS smoothens wrinkl...