The IL-6 -174G/C single nucleotide polymorphism (SNP) functionally affects IL-6 activity, with the G-allele associated with increased IL-6 levels. The C-allele was found to be associated with exercise-induced skeletal muscle damage. The aim of the present study was to examine the association between the IL-6 -174G/C polymorphism and athletic performance among elite swimmers and runners. The stu...

Brain cytokines, induced by various inflammatory challenges, have been linked to sickness behaviors, including fatigue. However, the relationship between brain cytokines and fatigue after exercise is not well understood. Delayed recovery of running performance after muscle-damaging downhill running is associated with increased brain IL-1beta concentration compared with uphill running. However, ...

Pacing strategies in marathon runners have previously been examined, especially with regard to age and performance level separately. However, less information about the age × performance interaction on pacing in age-group runners exists. The aim of the present study was to examine whether runners with similar race time and at different age differ for pacing. Data (women, n=117,595; men, n=180,4...

We investigated postural control (PC) effects of a mountain ultra-marathon (MUM): a 330-km trail run with 24000 m of positive and negative change in elevation. PC was assessed prior to (PRE), during (MID) and after (POST) the MUM in experienced ultra-marathon runners (n = 18; finish time = 126 ± 16 h) and in a control group (n = 8) with a similar level of sleep deprivation. Subjects were instru...

Garrett emphasized that all staff play a role in the streamlining effort and, more importantly, in the success of the university. “Whether we care for the campus grounds or maintain advanced research equipment, counsel students or manage payroll or process travel reimbursements, motivate donors or carry out the myriad of other ways and functions in which a research university operates, we are a...

We give a simple argument proving the lonely runner conjecture in the case where the speed of the runners forms a certain lacunary sequence. This improves an earlier result by Pandey, and is then used to derive that for each number of runners the lonely runner conjecture is true for a set of nonzero measure in a natural probability space.

Purpose Overuse injuries are common in recreational runners. Recent reports have implicated the characteristics of the footstrike in the etiology of stress responses in the tibia. This has motivated efforts to modify the loading at footstrike by altering the orientation of the foot at first contact. The present study aimed to: 1) report typical magnitudes of resultant tibial acceleration (TA) i...

Injury patterns in distance running may be related to kinematic adjustments induced by fatigue. The goal was to measure changes in lower extremity mechanics during an exhaustive run in individuals with and without a history of iliotibial band syndrome (ITBS). Sixteen recreational runners ran to voluntary exhaustion on a treadmill at a self-selected pace. Eight runners had a history of ITBS. Twe...

Experienced runners appear to naturally select a stride length which is optimal for minimizing oxygen uptake. However, whether this ability is naturally built into the human body or whether it is learned through experience has not been previously tested. This study investigated whether inexperienced runners are as capable as experienced runners of self-optimizing stride length to minimize oxyge...