flammatory process and reducing coronary artery damage [5–7] . However, despite the growing armamentarium of anti-inflammatory treatments, 5–10% of patients with Kawasaki disease are left with coronary artery injury, ranging from mild dilatation to severe and persistent aneurysms [8] . Mid-term follow-up into the second and third decade of life of children who have had normal echocardiograms pr...

The aim of this study was to determine risk factors for coronary lesions, the type of heart lesion present, and long-term outcome in Kawasaki disease. We studied 150 children, aged 3 months to 9.5 years, who met the criteria for a diagnosis of Kawasaki disease. Of the 18% who were diagnosed with heart disease, 100% had coronary artery abnormalities, 11.1% had pancarditis, and 3.7%, mitral insuf...

Kawasaki disease, also known as mucocutaneous lymph node syndrome or infantile polyarteritis nodosa is an acute febrile vasculitis of unknown etiology with a predilection for coronary arteries and potential for aneurysm formation. In Incomplete Kawasaki disease, children with fever lack the sufficient number of criteria to fulfill the epidemiologic case definition and are diagnosed when coronar...

Kawasaki disease is one of the most common vasculidities of childhood. It is the leading cause of acquired heart disease in children in the US.1 Although its course is typically self-limited, it is important that the clinician have a high degree of suspicion for its presence in light of its potential cardiac complications. It should be included in the differential diagnosis for any child with p...

Kawasaki disease is an acute vasculitic illness of childhood associated with significant morbidity and mortality. A cellular based enzyme linked immunosorbent assay (ELISA) was used to demonstrate the presence of antiendothelial cell antibodies in sera from children with Kawasaki disease. Twenty one of 32 patients with Kawasaki disease had raised IgM antibody titres and four had raised IgG anti...