Abstract Background Up to 30% of Crohn's Disease (CD) patients suffer from perianal fistula creating a high disease burden. Treating CD is challenging compared cryptoglandular fistula, which have significantly better wound healing response. Previous studies suggested epithelial mesenchymal transition as an inducer formation, markers were observed in tracts. However, most normal mucosa, thus dis...

Porokeratosis is a specific disorder of keratinization that has five major clinical types and shows a characteristic cornoid lamella on histopathology. Giant porokeratosis is considered to be a morphological variant of porokeratosis of mibelli. Malignant degeneration has been described in all forms of porokeratosis but highest risk is associated with linear and giant porokeratosis . We report a...

The effects of particle size uniformity and mill type used to grind corn were determined in three experiments. In Exp. 1, 120 pigs (47.8 kg initial BW) were used. Treatments were 1) a 40:60 blend of coarsely rolled (in a roller mill) and finely ground (in a hammermill) corn with a large standard deviation (sgw) of particle size (sgw of 2.7), 2) hammermilled corn with an sgw of 2.3, and 3) rolle...

Abstract A 1.5-year-old male Iberian lynx born in captivity presented with a 2.2 cm exophytic nodular alopecic mass at the left tarsus medial aspect, before being released into wild. The lesion had keratinised material protruding through 1.2 pore, forming cutaneous horn. Histopathology revealed cystic dermo-epidermal lined by psoriasiform hyperplasia of epithelium, thicker base cyst, together a...

Palmoplantar keratodermas are a heterogenous group of diseases, one of them is Papillon-Lefevre Syndrome (PLS). This rare disease is inherited as autosomal recessive and characterized by focal hyperkeratotic plaques on elbows and knees, severe periodontal disease resulting in premature loss of teeth. We report two brothers with PLS who did not have a history of this disease in their famil...