For the purpose of biochemical studies utilizing radioiodine 1131 as a tracer material, it is desirable to have a simple, sensitive, and thoroughly validated method for the measurement of the radioactivity of the biological samples. The present investigation was undertaken to provide such a method, with part,icular reference to the thyroid of the rat, but is adaptable with appropriate modificat...

It is hypothesized that dietary iodine deficiency is associated with the development of mammary pathology and cancer. A review of the literature on this correlation and of the author's own work on the antioxidant function of iodide in iodide-concentrating extrathyroidal cells is reported. Mammary gland is embryogenetically derived from primitive iodide-concentrating ectoderm, and alveolar and d...

Iodide, as a biologically important anion, it remains a worthwhile yet challenging undertaking to find a sensitive and specific approach to provide a technically simple iodide detection. In this article, it was found that no other ions than iodide-induced anisotropic growth of gold nanocrystals (AuNCs) originated from a small molecule, histidine-mediated synthesis of AuNCs, were observed. Simul...

A sensitive assay is developed to assess the existence of an iodide channel in a fraction of solubilized membrane proteins. This step is critical when considering various procedures for purification of this channel. Sodium cholate is used as a detergent as it does not denature the iodide channel. A simple and rapid method involving gel-filtration chromatography is used simultaneously to remove ...

BACKGROUND Perchlorate and thiocyanate interfere with iodide uptake at the sodium-iodide symporter and are potential disruptors of thyroid hormone synthesis. Perchlorate is a common contaminant of water, food, and human milk. Although it is known that iodide undergoes significant diurnal variations in serum and urinary excretion, less is known about diurnal variations of milk iodide levels. O...

The crystal structure of dl-alanine hydro-iodide (1-carb-oxy-ethanaminium iodide), C(3)H(8)NO(2) (+)·I(-), is that of an organic salt consisting of N-protonated cations and iodide anions. The compound features homochiral helices of N-H⋯O hydrogen-bonded cations in the [010] direction; neighbouring chains are related by crystallographic inversion centers and hence show opposite chirality. The io...

a simple and efficient one-pot method for the preparation of aromatic iodides has been developed by sequential diazotization–iodination of aromatic amines employing sodium nitrite and sodium iodide in the presence of acidic ionic liquid n-methyl-2-pyrrolidonum hydrosulfate ([h-nmp]hso4). the diazonium salts that are formed by this ionic liquid are stable at room temperature and react rapidly wi...

An experiment was designed to examine a mechanism to improve embryonic survival following maternal thyroid hormone manipulation. Commercial turkey breeder hens were fed diets containing supplemental iodide to mimic changes in the maternal thyroid output during an egg production cycle (32 to 48 wk of age). Dietary iodide treatment depressed maternal blood thyroxine (T4) concentrations in a time-...

An experiment was conducted to investigate the effect of thyroid gland activity modulation (Hyper or hypothyroidism) on energy utilization in broiler chickens. Two hundred and forty one-day-old Cobb broiler chicks were distributed into three dietary metabolizable energy (ME) treatment groups (80 chicks each). The control group (E0) was fed basal diet (3150 kcal/kg diet), the second group (E1) w...