The spectrum of "demyelinating disorders" is broad and it includes various disorders with central nervous system (CNS) demyelination[...].

German embryologist Viktor Hamburger [4] came to the US in 1932 with a fellowship provided by the Rockefeller Foundation [5]. Hamburger started his research in Frank Rattray Lillie?s laboratory at the University of Chicago [6]. His two-year work on the development of the central nervous system [7] (CNS) in chick [8] embryos was crystallized in his 1934 paper, ?The Effects of Wing Bud Extirpatio...

Guillain Barre Syndrome (GBS) is an autoimmune polyneuropathy. There is ascending paralysis seen in this and the onset is rapid, many a times preceded by an infection. Hyporeflex is observed and if respiratory component is involved can lead to death. Both sensory and autonomic nerve involvement is seen [1]. Matrix metalloproteinase (MMP’s) are the biggest family of extra cellular matrix degradi...

Introduction: Burkitt lymphoma (BL) is rare, but an aggressive malignancy. Central nervous system Burkitt lymphoma (CNSBL) is very rare. CNS Burkitt’s lymphoma is treated with high-dose chemotherapy and radiation. Radiotherapy in children younger than three years old may cause major CNS damage. Case report: A three-year-old boy presented with painful proptosis of the left eye. He under...

Astrocytoma as one of the most common central nervous system (CNS) tumors is rarely reported in veterinary literature. A 7-year-old Persian Lori-Bakhtiari ewe was presented to the clinic with a two months history of progressive blindness, nystagmus to the right, bilaterally decreased pupillary reflexes, head pressing and paddling. At necropsy, a whitish well-circumscribed mass with dimensions o...

MRI is currently the best imaging modality to assess myelin maturation in the human brain. Myelin is the insulator for nerves and is present in both the peripheral nervous system and the central nervous system (CNS). In the CNS, it is a modified extension of the oligodendrocyte cell and is made up of multiple sheaths of protein-lipid-protein-lipid-protein. Standard T1-weighted and T2-weighted s...

Central nervous system (CNS) infection is associated with high rates of morbidity and mortality, despite advancements in molecular testing, aseptic meningitis remains challenging to diagnose. Aseptic cases are often underreported worldwide, which impacts the quality patient care. Therefore, we aimed assess results BioFire® FilmArray® meningitis/encephalitis (ME) PCR panel, clinical characterist...

TDC: Tunneled Dialysis Catheter; GWE: Guidewire-Directed Exchange; MSSA: Methicillin-Sensitive Staphylococcus Aureus; MRSA: Methicillin-Resistant Staphylococcus Aureus; CNS: Coagulase-Negative Staphylococcus; VREF: VancomycinResistant Enterococcus Faecalis; ABE: Acute Bacterial Endocarditis; PE: Pulmonary Embolism; DVT: Deep Vein Thrombophlebitis (Central Vein); CNS: Central Nervous System; CNI...