Recently, open-domain dialogue systems have attracted growing attention. Most of them use the sequence-to-sequence (Seq2Seq) architecture to generate responses. However, traditional Seq2Seq-based models tend generic and safe responses, which are less informative, unlike human In this paper, we propose a simple but effective Keywords-guided Sequence-to-sequence model (KW-Seq2Seq) uses keywords i...

Abstract With the increasing of requirements from many aspects, various queries and analyses arise focusing on social network. Time is a common necessary dimension in types networks. Social networks with time information are called temporal networks, which can be when user sends message to another user. Keywords search consists finding relationships between group users that has set query labels...

Objectives We aimed to evaluate the global scientific output of gene research of myocardial infarction and explore their hotspots and frontiers from 2001 to 2015, using bibliometric methods. Methods Articles about the gene research of myocardial infarction between 2001 and 2015 were retrieved from the Web of Science Core Collection (WoSCC). We used the bibliometric method and Citespace V to a...

MicroRNAs (miRs) are non-coding ribonucleic acids consisting of about 18-22 nucleotide bases. Expression of several miRs can be altered in breast carcinomas in comparison to healthy breast tissue, or between various subtypes of breast cancer. These are regulated as either oncogene or tumor suppressors, this shows that their expression is misrepresented in cancers. Some miRs are specifically ass...

Background Type 2 diabetes and periodontitis predispose to a higher risk of severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection. Recent studies show upregulation innate immuno-regulatory microRNA-146a -155 in oral fluids patients with type as well periodontitis. The aim was investigate whether these microRNAs may relate patient susceptibility the infection via modulation SARS-C...

Delivery System for microRNA In article number 2104359, Xiaoxiao Cai and co-workers present a tetrahedral framework nucleic acids-based delivery system miRNA. miRNA is protected extracellularly, efficiently released in response to intracellular RNase after cellular entrance. Similarly, Chinese philosophy “Chuang Tzu” portrayed the transformation of legendary fish “Kun” (protected microRNA) into...

micrornas are 19-22 nucleotide rnas involved in such important processes as development, proliferation, differentiation and apoptosis. different mirnas are uniquely expressed in lymphoid t cells, and play a role indevelopment and differentiation of various subtypes by targeting their target genes. recent studies have shown that aberrant mirna expression may be involved in t cell leukemogenesis ...

context:micrornas (mirnas) are a class of short, endogenously-initiated, non-coding rnas that post-transcriptionally control gene expression via translational repression or mrna turnover. mirnas have attracted much attention in recent years as they play critical roles in gene expression and are promising tools with many biotech and therapeutic applications. the molecular mechanisms underlying t...