Wilms’ tumor (WT)/ Nephroblastoma is the second common abdominal malignancy and most common malignant renal tumor in children [1]. Twelve % of WT patients have metastases at initial presentation [2]. Common hematogenous metastatic site of WT include the lung, liver, and contralateral kidney. Less common sites include the bone, skin, brain, and orbit [2]. The lung is most common hematogenous met...

exudative retinal detachment (erd) may be seen with many ocular pathologies including malignancies. among malignant causes, metastases of breast and lung carcinoma are most common. a 50-year-old woman referred to our clinic with history of decreased visual acuity in her right eye since 3 months before referral. the visual acuity was counting fingers at 2 meters and 6/10 in the right and left ey...

Choriocarcinoma is a pure epithelial tumor composed of syncytiotrophoblastic and cytotrophoblastic cells with common metastases to the lung, vagina, liver, kidney, and brain [1]. Metastasis to the breast is very rare [2]. Since choriocarcinoma is a rapidly invasive, widely metastasizing malignancy with good response to chemotherapy, it is important to obtain early diagnosis for better outcome [...

Effective local ablation of large tumors with radiofrequency has been made possible by recent advancements. Tumor ablation with radiofrequency has been described mainly in the liver, but also recently in the kidney, adrenal gland, lung, and breast. A rapidly growing splenic metastasis from renal cell carcinoma was effectively treated percutaneously, with US guidance. Focal splenic disease may n...

PURPOSE Routine evaluation of kidney donors occasionally reveals an incidental renal mass with an otherwise satisfactory kidney function. The use of such a kidney with an enhancing mass for transplantation is a matter of debate owing to a possible risk of transmission of donor malignancies. We report our experience of kidney transplants from donors with renal cell carcinoma, after ex vivo resec...

Metastatic renal cell cancer is not exceptional in kidney cancer (30% of patients with kidneyl cancer). Its prognosis is particularly severe. However, sciatic neuralgia (sciatica) remains an exceptional revealing clinical sign of this disease. The authors report the case of a patient admitted with right sciatica as chief complain, leading to the discovery of a renal cell carcinoma. Although unc...

Solitary metastatic pancreatic lesions comprise 0.5% to 3% of all pancreas neoplasms, most commonly arising from primary tumors of the kidney, lung, or colon. Synchronous metastatic pancreatic lesions are exceptionally rare. Only 25 cases of isolated colorectal pancreatic metastasis amenable to resection have been reported, 11 of those in the distal pancreas. To our knowledge we report the firs...

malignant melanoma has the heart metastasis rate of 50 - 71%, which seems to be the highest among other malignancies. when a patient presents with cardiac metastases of melanoma, the disease has already spread through the body and therefore hardly curable. this brief review tried to introduce this important condition and discuss its frequency, presentation, diagnosis, histologic findings and tr...

Reported herein are simultaneous double primary clear cell carcinomas arising from liver and kidney. A 63-year-old man underwent a partial wedge nephrectomy of the right kidney in a surgical resection for hepatocellular carcinoma. Coincidently, on histology the tumors in liver and kidney were consisted of clear cancer cells, which arranged in haphazardly intermixed pattern without capsules. Imm...

Kisspeptin is originally a metastasis suppressor. Currently, post preliminary discovery, the crucial physiology of kisspeptin appeared among several biological function in living body such as supporting reproductive system, regulation metabolism, improvement cardiac muscle action and smooth blood vessels. Moreover, play an important role neurotransmitter through receptor. This study designed to...