Kruppel-like factor 4 (Klf4) is a member of the KLF family of transcription factors and regulates proliferation, differentiation, apoptosis and somatic cell reprogramming. In embryonic stem (ES) cells, Klf4 can be a good indicator of stem-like capacity. Klf4 is a 55 kD transcription factor containing three zinc finger domains. Klf4 binds the CACCC core sequence at multiple sites in the 5’ flank...
