Immune checkpoint inhibitors or anti-cancer immunotherapy using cellular transfer have emerged as new therapies in this field. These work to overcome alleviate tumour-induced immunosuppression, resulting immune-mediated tumour clearance. Cellular the largest number of active agents and clinical trials. More targets been explored, more trials opened patients recruited for a result recent advance...

18 Objectives: To monitor the stability of rifampicin (RIF) in Löwenstein-Jensen medium (L-J 19 medium) and 7H9 broth, which are the commonly used media for drug susceptibility testing (DST) 20 for Mycobacterium tuberculosis. Methods: Rifampicin degradation in stock solution, 7H9 broth, 21 L-J medium, and during the inspissation process for L-J medium preparation was serially 22 monitored by hi...

Background: Over-expression of CD117 and cytokeratin 20 (CK20) is seen in many malignancies. Given that few studies have been conducted regarding the role of these biomarkers in the etiology of bladder tumours, this study aimed to evaluate the prognostic value of CD117 and CK 20 biomarkers in the benign and malignant tumours of urinary bladder carcinoma. Methods: This case-control study was co...

PROGRESSION MODEL 2 3 Michael S. Nastasie, Helmut Thissen, David A. Jans and Kylie M. Wagstaff 4 Nuclear Signalling Laboratory, Dept. Biochemistry and Molecular Biology, Monash 5 University, Clayton, Victoria 3800, Australia 6 CSIRO Molecular and Health Technologies, Bayview Avenue, Clayton, Victoria 3168, 7 Australia 8 Running Title: Tumour selective nuclear targeting 9 10 *Correspondence shou...

This case series describes three unreported cases of an uncommon benign neoplasm named Abrikossoff’s tumour or granular cell tumour (GCT). This mesenchymal neoplasm apparently arises from neural or Schwann cell origin with benign and malignant forms. All cases presented here were unique nodules on oral mucosa, coming out from the connective tissue, and occurring in women with age ranging from 3...

introduction: salivary gland tumors (sgts) are important parts of human neoplasms. the most common sgt is pleomorphic adenoma and the most common malignant sgts are mucoepidermoid carcinoma and adenoid cystic carcinoma (acc). metastasis-associated genes 1 (mta1), a member of the nucleosome remodeling and histone deacetylation complex, is one newly discovered gene which recruits histone deacetyl...

Syringocystadenoma papilliferum is an uncommon benign apocrine gland tumour, mostly of congenital or early childhood onset, affecting head and neck. In addition, nevus sebaceous is commonly associated with this tumor. Here, we document three cases of syringocystadenoma papilliferum with many atypical features, such as the involvement of rare sites (abdomen, axilla and thigh), absence of nevus s...