This paper is covering new, simplistic method of obtaining the system for controlled delivery of the ascorbic acid. Copolymer poly (D,L-lactide-co-glycolide) (DLPLG) nanoparticles are produced using physical method with solvent/nonsolvent systems where obtained solutions were centrifuged. The encapsulation of the ascorbic acid in the polymer matrix is performed by homogenization of water and or...

Two high-performance liquid chromatography (HPLC) methods for ascorbic acid (AA) quantification were compared in three cultivars of melon (Cucumis melo L.) fruits. Both procedures were analogous except for the extraction medium used: 6 % meta-phosphoric acid and 3 % citric acid. The general conclusion is that 3 % citric acid is a better extraction medium compared to 6 % meta-phosphoric acid and...

Metabolic Alterations in the Squirrel Monkey Induced by DDT Administration and Ascorbic Acid Deficiency, CHADWICK, R. W., CRANMER, M. F., and PEOPLES, A. J. (1971). Toxicol. Appl. Pharmacol. 20, 308-318. A daily po injection of 5 mg of 1 ,l,l-trichloro-2,2-bis(pchlorophenyl)ethane (DDT) given to squirrel monkeys for a 2-wk period produces significant increases in liver weight, microsomal protei...

There have been numerous reports suggesting that the metabolism of ascorbic acid in humans and in animals is affected by stress.l However, detailed information which would permit an analysis of the underlying mechanism is not available. From the variety of effects cited, it would appear that no single mechanism can explain all of the findings. It has been suggested that increased ascorbic acid ...

Study on using ascorbic acid and ferrous reduction method to removal the chlorate ions (ClO3 ) in the water. The results show that 100 mL 3.06 mg/L of ClO3 in ascorbic acid and ClO3 quality ratio 7.19, pH =6.2,35°C, the reaction time of for 15 min, the removal rate was 100%. And ferrous reduction method to remove 100mL 3.06 mg/L of ClO3 in pH = 6.2, Fe and ClO3 quality ratio 1.79, 30°C for 30mi...

Human tumors may contain high concentrations of ascorbic acid, but little is known about how they acquire the vitamin. Certain specialized cells can transport ascorbic acid directly through a sodium ascorbate cotransporter, but in most cells, vitamin C enters through the facilitative glucose transporters (GLUTs) in the form of dehydroascorbic acid, which is then reduced intracellularly and reta...

the sulphated form of ascorbic acid may play a role in the maintenance of connective tissue, suggested that although 35S-labelled glycosaminoglycans are formed in the presence of ascorbic acid 2-[35S]sulphate, they are not formed by direct transfer of the sulphate moiety from ascorbic acid 2-[35S]sulphate but by a decomposition product of the ester (Shapiro & Poon, 1975). The role of ascorbic a...