There is a widely held view that the pace of change in by consultants who have received training in how to teach. However these changes to the postgraduate scene are Higher Education, particularly in the health care sector, has never been as rapid as it is at present. Of course this is the arguably dwarfed by the changes to undergraduate medical training. The General Medical Council has been ma...

The Human Proteome Organisation Proteomics Standards Initiative (HUPO-PSI) has recently published the Minimum Information About a Proteomics Experiment (MIAPE) specification. MIAPE is a set of documents aimed at formalizing the information or metadata that should be reported about a proteomics experiment, for example when it is published in a journal or a data set is deposited in a public data ...

Statins are now among the most widely used drugs in the world. They have proven efficacy in treating hyperlipidemia and in the prevention of vascular disease, with randomized data showing that they confer benefits in terms of clinical outcomes, including mortality. However, no drugs are without their adverse effects. The most well-known adverse effect of statins is probably muscle toxicity, whi...

A mathematical expression very similar to the entropy Sq, the basis of nonextensive statistical mechanics, was, to the best of my present knowledge, first introduced by J. Harvda and F. Charvat in 1967 and then again, independently, by Z. Daroczy in 1970. They did so in the context of cybernetics and control theory but apparently never found any application. In September 1985 in Mexico City, as...

Under the name prime decomposition (pd), a unique decomposition of an arbitrary N dimensional density matrix ρ into a sum of seperable density matrices with dimensions determined by the coprime factors of N is introduced. For a class of density matrices a complete tensor product factorization is achieved. The construction is based on the Chinese Remainder Theorem, and the projective unitary rep...

A Neutrino Factory based on a muon storage ring is the ultimate tool for studies of neutrino oscillations, including possibly the discovery of leptonic CP violation. It is also the first step towards a μμ collider. Ionization cooling of muons has never been demonstrated in practise but has been shown by end-to-end simulation and design studies to be an important factor both for the performance ...

TO THE EDITOR: Glancy et al. (4) measure the rate of oxygen consumption (Jo) by mitochondria incubated with an ATPconsuming system in the presence of creatine kinase (CK), and they show that this in vitro model of aerobically exercising skeletal muscle conforms to Meyer’s electrical analog of muscle oxidative phosphorylation in vivo (23). I want to suggest that the interpretation of these exper...

WHITE ADIPOSE TISSUE is no longer viewed as a somewhat unglamorous organ but has instead emerged as one of the current “hot spots” in physiological and biomedical research. Two key developments underlie this change. One is the rapid rise in the incidence of obesity, which now affects nearly one-third of adult Americans (2) and more than one in five of adults in the United Kingdom (14). Obesity ...

We present a new analytical description of the cellular automaton model for singlelane traffic. In contrast to previous approaches we do not use the occupation number of sites as dynamical variable but rather the distance between consecutive cars. Therefore certain longerranged correlations are taken into account and even a mean-field approach yields non-trivial results. In fact for the model w...

Randomised controlled trials and surveys of patients’ experiences indicate that the recognition and prompt treatment of early warning signs of relapse in selected patients with bipolar affective disorder are effective in lengthening the time to the next manic relapse and improving function. Improvements in patient coping mechanisms allied to these techniques can prevent some depressive episodes...