نتایج جستجو برای: labdan diterpenoid
تعداد نتایج: 1007 فیلتر نتایج به سال:
Anti-angiogenesis targeting vascular endothelial growth factor receptor-2 (VEGFR-2) has been considered as an important strategy for cancer therapy. Penduliflaworosin is a diterpenoid isolated from the plant Croton crassifolius. Our previous study showed that this diterpenoid possesses strong anti-angiogenic activity by inhibiting vessel formation in zebrafish. This study was conducted to furth...
The attention is focused on the “Chukurovo” lignites of the Sofia coal-bearing province. The coal sediments are of Neogene age: petrological studies have indicated a Badenian-Sarmatian age, while the paleobotanical interpretations have indicated the Karpatian-Badenian, respectively Early-Middle Miocene boundary. Fossilized trees are common in the Chukurovo lignites, as well as petrified wood ti...
Liverworts (Hepaticae) form a special group consi dered to be an early stage in the evolution of terrest rial plants, and produce terpenoids and/or aromatic compounds characteristic to the species as their ma jor lipophilic constituents. During the last two de cades many types of sesquiterpenoids have been ob tained from the liverworts and most of the liverwort sesquiterpenoids are the ena...
From the aerial parts of Salvia ballotiflora, eleven diterpenoids were isolated; among them, four icetexanes and one abietane (1-5) are reported for the first time. Their structures were established by spectroscopic means, mainly ¹H- and 13C-NMR, including 1D and 2D homo- and hetero-nuclear experiments. Most of the isolated diterpenoids were tested for their antiproliferative, anti-inflammatory...
Natural products offer unmatched chemical and structural diversity compared to other small-molecule libraries, but traditional natural product discovery programs are not sustainable, demanding too much time, effort, and resources. Here we report a strain prioritization method for natural product discovery. Central to the method is the application of real-time PCR, targeting genes characteristic...
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