Understanding the molecular organisation of intracellular signalling pathways is a topic of considerable research interest. Since many signalling enzymes are widely distributed and have several substrates, a critical component in signal transduction is the control of specificity. This is achieved, in part by the assembly of multiprotein complexes where clusters of signalling enzymes create foca...

A new Schiff base of 5-chloro-3-phenyl-1H-indole-2-carboxyhydrazide and 3-formyl-2-hydroxy-1H-quinoline (HL), and its Cu(II), Co(II), Ni(II), Zn(II), Cd(II), and Hg(II) complexes have been synthesized and characterized in the light of microanalytical, IR, H1 NMR, UV-Vis, FAB-mass, ESR, XRD, and TGA spectral studies. The magnetic susceptibility measurements and low conductivity data provide evid...

the present work is focused on the degradation of 4-chloro-2-nitrophenol in aqueous solution containing nano titanium dioxide, hydrogen peroxide and the combination of nano-tio2/h2o2. the effect of experimental parameters, such as the amount of nano- tio2 concentration of h2o2, initial concentration of 4-chloro-2-nitrophenol and ph on the reaction was investigated. experimental data obtained un...

A series of new copper(II), cobalt(II), nickel(II), manganese(II), iron(III), and uranyl(VI) complexes of the Schiff base hydrazone 7-chloro-4-(benzylidene-hydrazo)quinoline (HL) were prepared and characterized. The Schiff base behaves as a monobasic bidentate ligand. Mononuclear complexes with the general composition [ML2(Cl)m(H2O)2(OEt)n] x xEtOH (M = Cu(II), Co(II), Ni(II), Mn(II), Fe(III) o...

In this work, the theoretical studies on molecular structure are presented for 2-Acetyl-5-chloro-thiophene thiosemicarbazone and its Ni(II) Zn(II) complexes. The optimized geometry fundamental vibrational frequency values have been investigated with help of DFT/B3LYP method using 6-31G(d,p) basis set they found to be in agreement experimental values. Additionally, frontier orbital energies (HOM...

Five crystal structures of hydrogen-bonded complexes (N-(p-iodophenyl)-M-(p-cyanophenyl)melamine.barbital, N,M-diphenylmelamine.S,5-dimethylbarbituric acid, 2-amino-4( (m-bromophenyl)amino)-6-chloro-1,3,5-triazine.barbital, melamine.5,5-dibromobarbituric a id, and melamine.barbituric acid) are presented. These particular components represent perturbations on the molecules that were previously u...

Three copper(ii) coordination compounds have been prepared from three different 2,2':6',2''-terpyridine-based ligands, which have been selected to investigate the potential role of supramolecular interactions on the DNA-interacting and cytotoxicity properties of the corresponding metal complexes. Hence, the ligands 4'-((naphthalen-2-yl)methoxy)-2,2':6',2''-terpyridine () and 4'-((1H-benzo[d]imi...