Infrared laser irradiation has been established as an appropriate stimulus for primary sensory neurons under conditions where sensory receptor cells are impaired or lost. Yet, development of clinical applications has been impeded by lack of information about the molecular mechanisms underlying the laser-induced neural response. Here, we directly address this question through pharmacological cha...

We have investigated the effect of laser irradiation on the terrace morphology of Br-covered GaAs ~110!. Layer-by-layer etching of GaAs ~110! is demonstrated through laser-induced etching and atomic desorption. Nanosecond pulsed-laser irradiation ~hn52.3 eV, pulse power ;35 mJ cm! of Br–GaAs ~110! initially produces a high density of small, single-layer etch pits as Br is consumed. Continued la...

A malachite green-conjugated inositol 1,4,5-trisphosphate (MGIP(3)) induces specific inactivation of IP(3) receptor (IP(3)R) in tissue samples upon laser irradiation. To verify potential usefulness of the method for studies of cellular Ca(2+) signaling, we conducted laser inactivation at the single-cell level and show that IP(3)R was inactivated with extremely high spatiotemporal resolution. In...

Controlled modification of appropriate sharpness for nanotips is of paramount importance to develop novel materials and functional devices at a nanometer resolution. Herein, we present a reliable and unique strategy of laser irradiation enhanced physicochemical etching to manufacture super sharp tungsten tips with reproducible shape and dimension as well as high yields (~80%). The corresponding...

OBJECTIVE This study was conducted to investigate the effects of low-level laser (LLL) doses on human red blood cell volume. The effects of exposure to a diode pump solid state (DPSS) (λ = 405 nm) laser were observed. BACKGROUND DATA The response of human blood to LLL irradiation gives important information about the mechanism of interaction of laser light with living organisms. Materials and...

The controlled wettability of gold nanocomposite surfaces obtained by laser irradiation is introduced. Starting from the conception of materials with controlled surface properties, we describe all the different steps to generate the gold functionalized nanocomposite material and illustrate its surface wettability. Photopatterned gold polymeric films are performed in order to exhibit a remarkabl...

Pulsed femtosecond laser irradiation at low repetition rate, without any annealing, has been used to localize the growth of PbS nanoparticles, for the first time, inside a transparent porous silica matrix prepared by a sol-gel route. Before the irradiation, the porous silica host has been soaked within a solution containing PbS precursors. The effect of the incident laser power on the particle ...

Implant therapy can lead to peri-implantitis, and none of the methods used to treat this inflammatory response have been predictably effective. It is nearly impossible to treat infected surfaces such as TiUnite (a titanium oxide layer) that promote osteoinduction, but finding an effective way to do so is essential. Experiments were conducted to determine the optimum irradiation power for stripp...

Impaired wound healing is a common complication associated with diabetes with complex pathophysiological underlying mechanisms and often necessitates amputation. With the advancement in laser technology, irradiation of these wounds with low-intensity laser irradiation (LILI) or phototherapy, has shown a vast improvement in wound healing. At the correct laser parameters, LILI has shown to increa...

A photon-to-thermal conversion nanosystem has been developed to rapidly elevate temperatures in poorly thermally conducting media using irradiation of gold nanorods. We first hypothesized that nanoparticles, especially gold nanorods, are capable of generating enough heat to lyse bacteria by heating sample solutions via laser irradiation. To test this, we synthesized Au nanorods (aspect ratio 3-...