OBJECTIVE To evaluate the performance and cost efficacy of different first-trimester contingent screening strategies based on an initial analysis of biochemical markers. DESIGN Retrospective study. SETTING Swedish National Quality Register for prenatal diagnosis. POPULATION 35,780 women with singleton pregnancies. METHODS Serum values from first trimester biochemistry were re-analyzed i...

BACKGROUND Despite being associated with lower birth weight, maternal smoking in the last 2 trimesters of pregnancy has been associated with increased risk of offspring overweight in several studies. To date, only one study has examined whether smoking in the first trimester only, which is not associated with birth weight, is also associated with childhood overweight. OBJECTIVE This study use...

BACKGROUND Childbearing years in the women's life are associated with the highest risk of depression. In this study depression in third trimester of pregnancy and after delivery was studied. Depressive symptom score and the proportion of mothers above a threshold were compared to indicate probable depressive disorder at each stage. METHODS This prospective cohort study was conducted in rural ...

background: high maternal hemoglobin (hb) concentration was considered a risk factor for the developing of pregnancy hypertension. the purpose of this study was to determine whether high maternal hb concentration in first trimesters associated with pregnancy induced hypertension in iranian nulliparous women. methods: this study was carried out in teaching hospital in sari, iran. samples were ob...

Introduction: Anemia in pregnancy is a significant public health problem especially in developing countries. Iron deficiency anemia in pregnancy may lead to increased risks of preterm delivery, Low birth weight and still birth. This study was undertaken to detect iron deficiency anemia in pregnant women referring to health care centers of Eslamshahr/Iran. Method: In this study, 266 selected pre...

Pemphigoid gestationis (PG) is a rare autoimmune bullous dermatosis of pregnancy usually presents in the second or third trimester. It is characterized by pruritic, urticarial plaques with the development of tense vesicles and bullae within the lesions. Pathogenesis of PG is not fully established, however, most patients develop circulating autoantibodies targeting the bullous pemphigoid (BP) 18...

INTRODUCTION Prolonged pregnancy is associated with increased risk of pregnancy complications. The role of body mass index (BMI) is not completely identified in the risk of occurrence of prolonged pregnancy. The aim of this study was to determine the association between BMI and duration of pregnancy in woman referred to the Shariati Maternity Hospital in Bandar Abbas (Hormozgan Province, Iran)....

BACKGROUND HIV acquisition in pregnancy and breastfeeding contributes significantly toward pediatric HIV infection. However, little is known about how sexual behavior changes during pregnancy and postpartum periods which will help develop targeted HIV prevention and transmission interventions, including pre-exposure prophylaxis (PrEP). METHODS Cross-sectional study in HIV-infected and uninfec...

background: central nervous system malformations are the second most common congenital malformations after congenital heart diseases. these malformations are associated with many instances of morbidity and mortality which underline the importance of prevention and their early diagnosis. objective: the objective of this study is the diagnosis of neural tube defect (ntds) in the first trimester a...