Toxoplasma gondii is an obligate intracellular protozoan parasite that causes opportunistic disease, particularly in immunocompromised individuals. Central to its transmission and pathogenesis is the ability of the proliferative stage (tachyzoite) to convert into latent tissue cysts (bradyzoites). Encystment allows Toxoplasma to persist in the host and affords the parasite a unique opportunity ...

The diagnostic value of toxoplasma serology in ocular disease was evaluated in the following groups of patients: (I) uveitis cases of various causes (n = 291); (II) consecutive posterior and panuveitis patients (n = 60); (III) patients with definite congenital and ocular toxoplasmosis (n = 8); (IV) cases of clinical ocular toxoplasmosis (n = 25); and control patients with uveitis of non-toxopla...

Toxoplasmosis is a worldwide zoonosis that generally produces an asymptomatic infection. In some cases, however, toxoplasmosis infection can lead to ocular damage. The immune system has a crucial role in both the course of the infection and in the evolution of toxoplasmosis disease. In particular, IFN-gamma plays an important role in resistance to toxoplasmosis. Polymorphisms in genes encoding ...

Feline enteric coronavirus (FECV) infects enterocytes and causes inflammation of the intestinal mucosa in young cats, resulting diarrhea. In adult cats infection is usually asymptomatic, but constant circulation FECV feline population increases likelihood mutation, as a result which about 5-10% infected develop virulent strain virus that lethal infectious peritonitis – FIP. The purpose this stu...

Manuls or Pallas' cats (Felis manul, syn. Otocolobus manul) are endangered wild cats from Central Asia kept and bred in many zoos. Despite good breeding success young cats frequently die from acute toxoplasmosis. From 1998 to 2002, a breeding pair in the Schönbrunn Zoo in Vienna, Austria, gave birth to 24 kittens; 58 % of kittens died between the 2nd and the 14th week of life, mostly due to acu...

The latex agglutination test for toxoplasmosis was performed on 690 blood samples collected from the Veterans and Bang Bua Thong Hospitals in Bangkok. Blood samples were collected in the first- and the third-trimester from pregnant women and from the cord blood. The seroprevalence of toxoplasmosis in the first trimester was 13.14%, 13.60%; in the third trimester was 12.21%, 9.43% and in the cor...

BACKGROUND Ocular toxoplasmosis is a potentially blinding cause of posterior uveitis. Retinal detachment is rare complication of ocular toxoplasmosis. AIM To report the clinical course and prognosis of retinal breaks and detachments occurring in patients with ocular toxoplasmosis. PATIENTS AND METHODS This study was a retrospective, non-comparative case series of five patients with ocular t...

Ocular toxoplasmosis is a common vision-threatening disease in Indonesia. Diagnosis of this disease is based on characteristic ophthalmoscopic appearances and laboratory findings. Between 1985 and 1989, the authors retrospectively evaluated 41 children under 12 years of age. Thirteen cases had retinal lesions suspected to be toxoplasmosis but the laboratory findings were negative. The remaining...

OBJECTIVE to analyze the factors associated to toxoplasmosis-related knowledge among pregnant women attending public health services in the municipality of Niterói, Rio de Janeiro, Brazil. METHODS this is a cross-sectional study conducted with pregnant women assisted in eight health care units; data was collected using a standardized questionnaire, from April 2013 to February 2015. RESULTS ...

The protozoan parasite Toxoplasma gondii infects more than a billion people worldwide. The parasite is generally divided into three clonal lineages, denoted type I, II and III. Primary infections in humans are usually asymptomatic or characterized by non-specific symptoms, and are followed by latent chronic infection, which is normally harmless to the host. However, if the immune system is supp...