Learners have different knowledge, interests and also goals in any educational process. If all the learners are provided the same content the process will probably not meet expected goals. A personalized approach to a learner increases the efficiency of the learning process. It is based on information about the learner that is subject of change. Several adaptive educational systems exist. Howev...

Gastrointestinal xanthomas are characterized by foamy cytoplasmic cells containing lipid in lamina propria, and occur almost in the gastric mucosa. Colonic xanthomas have been described in rare case. All reported colonic xanthomas were located in rectosigmoid. Rectosigmoid xanthomas have tended to exhibit small polypoid lesion, on the contrary flat in stomach. We report a case of xanthoma on as...

OBJECTIVE To investigate whether or not the lesions in sporadic amyotrophic lateral sclerosis (ALS) originate from a single focal onset site and spread contiguously by prion-like cell-to-cell propagation in the rostrocaudal direction along the spinal cord, as has been hypothesised (the 'single seed and simple propagation' hypothesis). METHODS Subjects included 36 patients with sporadic ALS an...