Deep Neural Networks (DNNs) have recently been shown to be vulnerable against adversarial examples, which are carefully crafted instances that can mislead DNNs to make errors during prediction. To better understand such attacks, a characterization is needed of the properties of regions (the so-called ‘adversarial subspaces’) in which adversarial examples lie. In particular, effective measures a...

IZAKI A., SHIMO-OKU M. Deparfment of Ophthalmology, Hyogo College of Medicine (Japan) Puroose : Blink reflexes evoked with comeal sensation or flash light stimulation are widely performed to examine optic, trigeminal and facial nerve. Both the electro-oculographic findings of lid movements and scleral search coil findings of eye movements during those blinks were investigated previously, we stu...

Isolated unilateral congenital ptosis is encountered relatively infrequently in clinical practice. It typically consists of a unilateral droopy eyelid, weak levator palpebrae superioris muscle function, lid lag, and an absent upper lid crease with no other abnormalities on examination. We present a four-and-a-half-year-old girl with isolated and mild unilateral congenital ptosis who unexpectedl...

Phonotactic language identification (LID) by means of n-gram statistics and discriminative classifiers is a popular approach for the LID problem. Low-dimensional representation of the n-gram statistics leads to the use of more diverse and efficient machine learning techniques in the LID. Recently, we proposed phototactic iVector as a low-dimensional representation of the n-gram statistics. In t...

The 26S proteasome is responsible for the selective, ATP-dependent degradation of polyubiquitinated cellular proteins. Removal of ubiquitin chains from targeted substrates at the proteasome is a prerequisite for substrate processing and is accomplished by Rpn11, a deubiquitinase within the 'lid' sub-complex. Prior to the lid's incorporation into the proteasome, Rpn11 deubiquitinase activity is ...

Ocular dominance (OD) plasticity is a robust paradigm for examining the functional consequences of synaptic plasticity. Previous experimental and theoretical results have shown that OD plasticity can be accounted for by known synaptic plasticity mechanisms, using the assumption that deprivation by lid suture eliminates spatial structure in the deprived channel. Here we show that in the mouse, r...

Automatic Language Identification (LID) is the process of identifying the language spoken within an utterance. The challenge that this task presents is that no prior information is available indicating the content of the utterance or the identity of the language. Most of the existing LID systems are based on MFCC feature vectors. This paper introduces the use of new feature extraction approach ...

An upper lid eccrine hidrocystoma presenting as early childhood progressive ptosis is very rare. We present a 9-year-old female child with droopy right upper lid since birth and progressive increase in symptoms. She had right upper lid ptosis (marginal reflex distance 1 of -1 mm) with fair levator function (8 mm) and abnormal cystic change on the conjunctival side. Computerized tomography imagi...

Chaperonins use ATPase cycling to promote conformational changes leading to protein folding. The prokaryotic chaperonin GroEL requires a cofactor, GroES, which serves as a "lid" enclosing substrates in the central cavity and confers an asymmetry on GroEL required for cooperative transitions driving the reaction. The eukaryotic chaperonin TRiC/CCT does not have such a cofactor but appears to hav...

The key to enzyme function is the maintenance of an appropriate balance between molecular stability and structural flexibility. The lid domain which is very important for "interfacial activation" is the most flexible part in the lipase structure. In this work, rational design was applied to explore the relationship between lid rigidity and lipase activity by introducing a disulfide bond in the ...