CONTEXT "Low-risk" branch duct intraductal papillary mucinous neoplasm (IPMN) is defined as pancreatic epithelial cellular proliferation of small branch ducts that lack malignant characteristics. At present, our understanding of the natural history of "low-risk" branch duct IPMN is still evolving. Lady Windermere syndrome is a disorder seen in non-smoking women with no pre-existing pulmonary di...

Recent studies implicate the cerebellum, long considered strictly a motor control structure, in cognitive, sensory, and affective phenomenon. The cerebellum, a phylogenetically ancient structure, has reciprocal ancient connections to the hypothalamus, a structure important in vegetative functions. The present study investigated whether the cerebellum was involved in vegetative functions and the...

A 40 year old man, the son of nonconsanguineous healthy parents of Arab extraction, was hospitalized in our department because of left leg cellulitis. His medical history included bronchiectasis complicated by recurrent respiratory tract infections that necessitated lobectomy at age 20. Since adolescence he had suffered from swollen feet with recurrent leg cellulitis. The patient also displayed...

This study investigates the time course and regional differences in age-related volume loss in cerebellum and brainstem. Three-dimensional (3D) magnetic resonance imaging (MRI) volumetry was used to measure the volumes of 11 regions in the cerebellum and three regions in the brainstem in 48 healthy volunteers (age 19.8-73.1 years). Landmark-adjusted lattices were used to divide the cerebellum i...

BACKGROUND Clinical interpretation of bronchoalveolar lavage fluid results is dependent on the availability of reference values for healthy individuals. Only a few studies have published such reference values and the applicability of results is restricted by small sample sizes and the limited representativeness of the study population. We aim to investigate the influence of age, gender, collect...

BACKGROUND Radiofrequency ablation (RFA) is a thermal energy delivery system used for coagulative cellular destruction of small tumors through percutaneous or intraoperative application of its needle electrode to the target area, and for assisting partial resection of liver and kidney. We tried to evaluate the regional oxidative and pre-inflammatory stress of RFA-assisted wedge lung resection, ...

Background: Chronic interstitial lung diseases in children (chILD) are a heterogeneous group of disorders that can represent a clinical challenge for pediatric pneumologists. Among them, neuroendocrine cell hyperplasia of infancy (NEHI) is a diffuse lung disease prevalent in the first years of life that spontaneously improves over time. The clinical presentation of NEHI is indistinguishable fro...

OBJECTIVES The present study was designed to identify the effect of positive end expiratory pressure (PEEP) and the ideal pulmonary tidal volume to ventilate animals with a surgically produced bronchopleural fistula, aiming to reduce fistula output without affecting gas exchange. METHODS Hemodynamic and respiratory assessment of gas exchange was obtained in five, healthy, young, mechanically ...

Why map the cerebellar surface? Because: (i) organization of motor, sensory and cognitive functions in the human cerebellum is poorly understood [1], (ii) the highly-folded structure conceals most of the cortical surface, and (iii) functional data analysis may improve with incorporation of surface organization [2]. We constructed a pipeline for extracting, labelling, and conformally mapping cer...

Inflammation is a hallmark of bronchial asthma. Inflammatory cells both in bronchoalveolar lavage (BAL) and bronchial biopsies of asthmatic patients have been studied and correlated with functional or clinical parameters. We have recently attempted to assess airway inflammation by a visual endoscopic scoring system. The purpose of this study was to compare our own endoscopic scoring system with...