CD4(+)CD25(+) regulatory T (Treg) cells play a pivotal role in the maintenance of immune homeostasis, where the X-linked master transcription factor forkhead box P3 (FOXP3) determines Treg cell development and function. Genetic deficiency of foxp3 induces dysfunction of Treg cells and immuno-dysregulation, polyendocrinopathy, enteropathy, and X-linked syndrome in humans. Functionally deficient ...

primary immunodeficiencies (pid) are a group of disorders, characterized by an unusual susceptibility to infections. delay in diagnosis results in increased morbidity and mortality in affected patients. the purpose of this study was to determine the mortality rate of iranian immunodeficient patients referred to children medical center hospital affiliated to tehran university of medical sciences...

FPGAs can be used for the design of autonomic reliable systems. Advantages are reconfiguration and flexibility in the design. However commercial FPGAs are first prone to errors. Second, the design flow is not yet supported for the use of fault tolerance techniques like Built-In Self-Tests. Fault tolerance can be reached through error detection and fault recovery. Most error detection techniques...